Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology.
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The footprint of genome architecture in the largest genome expansion in RNA virusesThe Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate ResponseCoronavirus virulence genes with main focus on SARS-CoV envelope geneDimeric Structure of Pseudokinase RNase L Bound to 2-5A Reveals a Basis for Interferon-Induced Antiviral ActivityCrystal structure of the mouse hepatitis virus ns2 phosphodiesterase domain that antagonizes RNase L activationThe Role of Phosphodiesterase 12 (PDE12) as a Negative Regulator of the Innate Immune Response and the Discovery of Antiviral Inhibitors.Myelin-specific proteins: a structurally diverse group of membrane-interacting molecules.RNase L targets distinct sites in influenza A virus RNAs.Ribonuclease L mediates the cell-lethal phenotype of double-stranded RNA editing enzyme ADAR1 deficiency in a human cell line.PKR mediated regulation of inflammation and IL-10 during viral encephalomyelitis.Viral phosphodiesterases that antagonize double-stranded RNA signaling to RNase L by degrading 2-5ACoronavirus infection, ER stress, apoptosis and innate immunityWanderings in biochemistry.Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene.Interferon-induced protein Ifit2 protects mice from infection of the peripheral nervous system by vesicular stomatitis virus.Murine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis.Coronaviruses: an overview of their replication and pathogenesis.Evasion of antiviral innate immunity by Theiler's virus L* protein through direct inhibition of RNase LDefective viral genomes arising in vivo provide critical danger signals for the triggering of lung antiviral immunityRibonuclease L and metal-ion-independent endoribonuclease cleavage sites in host and viral RNAs.The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU.Overlapping Patterns of Rapid Evolution in the Nucleic Acid Sensors cGAS and OAS1 Suggest a Common Mechanism of Pathogen Antagonism and Escape.Enzyme assays for synthesis and degradation of 2-5As and other 2'-5' oligonucleotides.Structural basis for 2'-5'-oligoadenylate binding and enzyme activity of a viral RNase L antagonist.Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress ResponsesIdentification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG-I.Structural aspects of nucleotide ligand binding by a bacterial 2H phosphoesteraseEarly endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replicationActivation of RNase L is dependent on OAS3 expression during infection with diverse human virusesActivation of RNase L by Murine Coronavirus in Myeloid Cells Is Dependent on Basal Oas Gene Expression and Independent of Virus-Induced InterferonA review of genetic methods and models for analysis of coronavirus-induced severe pneumonitis.Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.Functional analysis of the murine coronavirus genomic RNA packaging signal.Interplay between viruses and host mRNA degradationCoronavirus receptor switch explained from the stereochemistry of protein-carbohydrate interactions and a single mutationCell-type-specific activation of the oligoadenylate synthetase-RNase L pathway by a murine coronavirus.Silencing the alarms: Innate immune antagonism by rotavirus NSP1 and VP3Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity.Alphacoronavirus protein 7 modulates host innate immune response.Soluble interleukin-6 receptor-mediated innate immune response to DNA and RNA viruses.
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P2860
Antagonism of the interferon-induced OAS-RNase L pathway by murine coronavirus ns2 protein is required for virus replication and liver pathology.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Antagonism of the interferon-i ...... plication and liver pathology.
@en
Antagonism of the interferon-i ...... plication and liver pathology.
@nl
type
label
Antagonism of the interferon-i ...... plication and liver pathology.
@en
Antagonism of the interferon-i ...... plication and liver pathology.
@nl
prefLabel
Antagonism of the interferon-i ...... plication and liver pathology.
@en
Antagonism of the interferon-i ...... plication and liver pathology.
@nl
P2860
P50
P1433
P1476
Antagonism of the interferon-i ...... plication and liver pathology.
@en
P2093
John Ziebuhr
P2860
P304
P356
10.1016/J.CHOM.2012.04.011
P577
2012-06-01T00:00:00Z