Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
about
The human polycystin-2 protein represents an integral membrane protein with six membrane-spanning domains and intracellular N- and C-terminiA polycystin-centric view of cyst formation and disease: the polycystins revisitedStructure of the EF-hand domain of polycystin-2 suggests a mechanism for Ca2+-dependent regulation of polycystin-2 channel activityA high-resolution structure of the EF-hand domain of human polycystin-2Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2Function and regulation of TRPP2 ion channel revealed by a gain-of-function mutantMolecular architecture and subunit organization of TRPA1 ion channel revealed by electron microscopyDeterminants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A.Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.Structural biology of TRP channels.Polycystin-1, 2, and STIM1 interact with IP(3)R to modulate ER Ca release through the PI3K/Akt pathwayCalcium-induced conformational changes in C-terminal tail of polycystin-2 are necessary for channel gating.Ion channels in renal disease.An explicit formulation approach for the analysis of calcium binding to EF-hand proteins using isothermal titration calorimetry.Decrypting the Heat Activation Mechanism of TRPV1 Channel by Molecular Dynamics Simulation.X-ray crystallography of TRP channels.Structural biology of TRP channels
P2860
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P2860
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
@en
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
@nl
type
label
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
@en
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
@nl
prefLabel
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
@en
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
@nl
P2093
P2860
P356
P1476
Ca2+-dependent conformational changes in a C-terminal cytosolic domain of polycystin-2.
@en
P2093
Frank Schumann
Helen Hoffmeister
Maren Schmidt
Reto Bader
P2860
P304
24372-24383
P356
10.1074/JBC.M109.025635
P407
P577
2009-06-22T00:00:00Z