The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents.
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The H19 Long non-coding RNA in cancer initiation, progression and metastasis - a proposed unifying theoryEndoreplication and polyploidy: insights into development and diseaseInvolvement of Receptor Activator of Nuclear Factor-κB Ligand (RANKL)-induced Incomplete Cytokinesis in the Polyploidization of Osteoclasts.Par1b induces asymmetric inheritance of plasma membrane domains via LGN-dependent mitotic spindle orientation in proliferating hepatocytesHepatoprotective effect of MMP-19 deficiency in a mouse model of chronic liver fibrosisPhosphorylated Ribosomal Protein S6 Is Required for Akt-Driven Hyperplasia and Malignant Transformation, but Not for Hypertrophy, Aneuploidy and Hyperfunction of Pancreatic β-CellsTGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis FailureThe normal mechanisms of pregnancy-induced liver growth are not maintained in mice lacking the bile acid sensor Fxr.Quantification of age-dependent somatic CAG repeat instability in Hdh CAG knock-in mice reveals different expansion dynamics in striatum and liverSingle-cell analysis of ploidy and centrosomes underscores the peculiarity of normal hepatocytes.The ploidy conveyor of mature hepatocytes as a source of genetic variation.Isoform-specific functions of Mud/NuMA mediate binucleation of Drosophila male accessory gland cells.Oxidative stress promotes pathologic polyploidization in nonalcoholic fatty liver disease.Multi-nucleate retinal pigment epithelium cells of the human macula exhibit a characteristic and highly specific distribution.Involvement of atypical transcription factor E2F8 in the polyploidization during mouse and human decidualization.p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and agingHepatocytes polyploidization and cell cycle control in liver physiopathology.p53 regulates a mitotic transcription program and determines ploidy in normal mouse liverLiver repopulation and regeneration: new approaches to old questions.To divide or not to divide: revisiting liver regeneration.Cellular homeostasis and repair in the mammalian liver.MicroRNA-122 regulates polyploidization in the murine liver.Hepatocyte polyploidization and its association with pathophysiological processesA structural basis for cellular senescence.Liver polyploidy: Dr Jekyll or Mr Hide?Hepatic regenerative medicine: exploiting the liver's will to live.Pathological polyploidy in liver disease.Hepatocyte Ploidy Is a Diversity Factor for Liver Homeostasis.Circadian clock regulates hepatic polyploidy by modulating Mkp1-Erk1/2 signaling pathway.Knockdown of Anillin Actin Binding Protein Blocks Cytokinesis in Hepatocytes and Reduces Liver Tumor Development in Mice without Affecting Regeneration.The Polyploid State Plays a Tumor-Suppressive Role in the Liver.Hippo Signaling Suppresses Cell Ploidy and Tumorigenesis through Skp2.Developmental Exposure to 2,2',4,4'-Tetrabromodiphenyl Ether Induces Long-Lasting Changes in Liver Metabolism in Male Mice.Emerging Role of mTOR Signaling-Related miRNAs in Cardiovascular Diseases
P2860
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P2860
The insulin/Akt pathway controls a specific cell division program that leads to generation of binucleated tetraploid liver cells in rodents.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
The insulin/Akt pathway contro ...... aploid liver cells in rodents.
@en
The insulin/Akt pathway contro ...... aploid liver cells in rodents.
@nl
type
label
The insulin/Akt pathway contro ...... aploid liver cells in rodents.
@en
The insulin/Akt pathway contro ...... aploid liver cells in rodents.
@nl
prefLabel
The insulin/Akt pathway contro ...... aploid liver cells in rodents.
@en
The insulin/Akt pathway contro ...... aploid liver cells in rodents.
@nl
P2093
P2860
P356
P1476
The insulin/Akt pathway contro ...... raploid liver cells in rodents
@en
P2093
Chantal Desdouets
Dominique Couton
Germain Margall-Ducos
Grégory Merlen
Séverine Celton-Morizur
P2860
P304
P356
10.1172/JCI38677
P407
P577
2009-07-01T00:00:00Z