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The rs10993994 risk allele for prostate cancer results in clinically relevant changes in microseminoprotein-beta expression in tissue and urineThe LIM domain protein LMO4 interacts with the cofactor CtIP and the tumor suppressor BRCA1 and inhibits BRCA1 activityThreonine 391 phosphorylation of the human prolactin receptor mediates a novel interaction with 14-3-3 proteinsTargeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancerPatient-derived xenograft models of breast cancer and their predictive powerEssential role for a novel population of binucleated mammary epithelial cells in lactation.CPAP interacts with 14-3-3 in a cell cycle-dependent mannerMutational analysis of the LMO4 gene, encoding a BRCA1-interacting protein, in breast carcinomasCancer stem cells in solid tumours: accumulating evidence and unresolved questionsDefective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1Generation of a functional mammary gland from a single stem cellDimerization of CtIP, a BRCA1- and CtBP-interacting protein, is mediated by an N-terminal coiled-coil motif.New Monoclonal Antibodies to Defined Cell Surface Proteins on Human Pluripotent Stem Cells.Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathwaysTargeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT studyThe LIM domain gene LMO4 inhibits differentiation of mammary epithelial cells in vitro and is overexpressed in breast cancer.E2F4 is exported from the nucleus in a CRM1-dependent manner.Breast-cancer risk in families with mutations in PALB2StarD10, a START domain protein overexpressed in breast cancer, functions as a phospholipid transfer protein.Analysis of cancer risk and BRCA1 and BRCA2 mutation prevalence in the kConFab familial breast cancer resource.Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation.Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraitsThe future of mammary stem cell biology: the power of in vivo transplants.Macrophages, more than just scavengers: their role in breast development and cancer.Delineating the epithelial hierarchy in the mouse mammary gland.Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer.Isolation of mouse mammary epithelial subpopulations: a comparison of leading methods.The mammary stem cell hierarchy.Differential hypermethylation of SOCS genes in ovarian and breast carcinomas.Targeting BCL-2 to enhance vulnerability to therapy in estrogen receptor-positive breast cancer.Preferences for breast cancer risk reduction among BRCA1/BRCA2 mutation carriers: a discrete-choice experiment.EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.Mainstreaming cancer genetics: A model integrating germline BRCA testing into routine ovarian cancer clinics.Patient and medical barriers preclude uptake of tamoxifen preventative therapy in women with a strong family history.Patient-derived xenograft (PDX) models in basic and translational breast cancer research.Out-RANKing BRCA1 in Mutation Carriers.
P50
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P50
description
hulumtues
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researcher
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հետազոտող
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoff Lindeman
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Geoffrey John Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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Geoffrey J. Lindeman
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P106
P1153
7003980203
P21
P31
P496
0000-0001-9386-2416