Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14. - Wikidata - wikimedia - TriplyDB

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

http://www.wikidata.org/entity/Q35531064

about

Mammary stem cells and the differentiation hierarchy: current status and perspectives Pregnancy-induced noncoding RNA (PINC) associates with polycomb repressive complex 2 and regulates mammary epithelial differentiation Infrequent loss of luminal differentiation in ductal breast cancer metastasis Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity GATA3 suppresses metastasis and modulates the tumour microenvironment by regulating microRNA-29b expression.Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland.GATA3 and TRPS1 are distinct biomarkers and prognostic factors in breast cancer: database mining for GATA family members in malignancies Computational analysis identifies a sponge interaction network between long non-coding RNAs and messenger RNAs in human breast cancer.RARRES3 suppresses breast cancer lung metastasis by regulating adhesion and differentiation GATA3 in the urinary bladder: suppression of neoplastic transformation and down-regulation by androgens Runx2 is a novel regulator of mammary epithelial cell fate in development and breast cancer The mammary cellular hierarchy and breast cancer.Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth Ror2 regulates branching, differentiation, and actin-cytoskeletal dynamics within the mammary epithelium.Mechanisms governing metastatic dormancy and reactivation.RUNX1, a transcription factor mutated in breast cancer, controls the fate of ER-positive mammary luminal cells.PVT1: a rising star among oncogenic long noncoding RNAs.A pooled shRNA screen for regulators of primary mammary stem and progenitor cells identifies roles for Asap1 and Prox1.Integration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraits The molecular landscape of premenopausal breast cancer.A Long-Lived Luminal Subpopulation Enriched with Alveolar Progenitors Serves as Cellular Origin of Heterogeneous Mammary Tumors.Stem and progenitor cell division kinetics during postnatal mouse mammary gland development A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis.Hypoxia-inducible factor 1α promotes primary tumor growth and tumor-initiating cell activity in breast cancer BMP-binding protein twisted gastrulation is required in mammary gland epithelium for normal ductal elongation and myoepithelial compartmentalization.Expression of caspase 14 and filaggrin in oral squamous carcinoma.Evidence for a multipotent mammary progenitor with pregnancy-specific activity.Loss of GATA3 in bladder cancer promotes cell migration and invasion.Transposon insertional mutagenesis in mice identifies human breast cancer susceptibility genes and signatures for stratification.RUNX2 in mammary gland development and breast cancer.The Significance and Therapeutic Potential of GATA3 Expression and Mutation in Breast Cancer: A Systematic Review.Regulation of antiapoptotic and cytoprotective pathways in colonic epithelial cells in ulcerative colitis.GATA3 expression in triple-negative breast cancers.ZNF503/Zpo2 drives aggressive breast cancer progression by down-regulation of GATA3 expression.Pubertal Mammary Gland Development: Elucidation of In Vivo Morphogenesis Using Murine Models.EGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.S100A7 acts as a dual regulator in promoting proliferation and suppressing squamous differentiation through GATA-3/caspase-14 pathway in A431 cells.Cell lineage determinants as regulators of breast cancer metastasis.Caspase 14 does not influence intestinal epithelial cell differentiation.EZH2 promotes a bi-lineage identity in basal-like breast cancer cells.

P2860

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P2860

Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14.

http://www.wikidata.org/entity/Q35531064

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Gata-3 negatively regulates th ...... e tumor suppressor caspase-14.

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Gata-3 negatively regulates th ...... e tumor suppressor caspase-14.

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Molecular and Cellular Biology

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Gata-3 negatively regulates th ...... e tumor suppressor caspase-14.

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P2093

David E Gyorki

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Di Wu

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François Vaillant

http://www.w3.org/2001/XMLSchema#string

Jane E Visvader

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Kelsey Breslin

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Marie-Liesse Asselin-Labat

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Mary L Bath

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Sheridan Holroyd

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Siddhartha Deb

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Teresa Ward

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P2860

Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours

Bioconductor: open software development for computational biology and bioinformatics

GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis

GATA-3 maintains the differentiation of the luminal cell fate in the mammary gland

GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

Molecular portraits of human breast tumours

Repeated observation of breast tumor subtypes in independent gene expression data sets

Processing of native caspase-14 occurs at an atypical cleavage site in normal epidermal differentiation

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4609-4622

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10.1128/MCB.05766-11

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22

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31

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Geoffrey J. Lindeman

Kate D Sutherland

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2011-09-19T00:00:00Z

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21930782

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3209243

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