One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. - Wikidata - wikimedia - TriplyDB

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

http://www.wikidata.org/entity/Q42419006

about

Large animal models of cardiovascular disease Gene targeting, genome editing: from Dolly to editors CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases Classification and evolution of type II CRISPR-Cas systems Off-target Effects in CRISPR/Cas9-mediated Genome Engineering Current progress of genetically engineered pig models for biomedical research Efficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into Zygotes Perspectives on avian stem cells for poultry breeding Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos Highly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigs Highly efficient generation of biallelic reporter gene knock-in mice via CRISPR-mediated genome editing of ESCs Efficient and versatile CRISPR engineering of human neurons in culture to model neurological disorders A CRISPR toolbox to study virus-host interactions Generating Mouse Models Using CRISPR-Cas9-Mediated Genome Editing.Cellular function reinstitution of offspring red blood cells cloned from the sickle cell disease patient blood post CRISPR genome editing Genetically modified pig models for neurodegenerative disorders.Myostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect.Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts.Myotube differentiation in clustered regularly interspaced short palindromic repeat/Cas9-mediated MyoD knockout quail myoblast cells.Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting.CRISPR/Cas9-mediated ApoE-/- and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels.The potential of the combination of CRISPR/Cas9 and pluripotent stem cells to provide human organs from chimaeric pigs.The production of multi-transgenic pigs: update and perspectives for xenotransplantation.An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system.The meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjection Efficient gene targeting in golden Syrian hamsters by the CRISPR/Cas9 system.A CRISPR view of development.Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers.Next-generation models of human cardiogenesis via genome editing Efficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA.CRISPR/Cas9 as tool for functional study of genes involved in preimplantation embryo development.Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem Cells Efficient gene knockout in goats using CRISPR/Cas9 system.Rosa26 locus supports tissue-specific promoter driving transgene expression specifically in pig.Review on porcine endogenous retrovirus detection assays--impact on quality and safety of xenotransplants Cloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.piRNAs from Pig Testis Provide Evidence for a Conserved Role of the Piwi Pathway in Post-Transcriptional Gene Regulation in Mammals.Brains, genes, and primates.Potential of promotion of alleles by genome editing to improve quantitative traits in livestock breeding programs.Eliminate mitochondrial diseases by gene editing in germ-line cells and embryos.

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P2860

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

http://www.wikidata.org/entity/Q42419006

description

2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

@zh-tw

2014年论文

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2014年论文

@zh

2014年论文

@zh-cn

name

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

@en

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

@nl

type

label

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

@en

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

@nl

prefLabel

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

@en

One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

@nl

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One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.

@en

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Fei Teng

http://www.w3.org/2001/XMLSchema#string

Qi Zhou

http://www.w3.org/2001/XMLSchema#string

Runfa Guo

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Tang Hai

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Wei Li

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P2860

Cas9 as a versatile tool for engineering biology

RNA-guided human genome engineering via Cas9

Multiplex genome engineering using CRISPR/Cas systems

Knockout rats via embryo microinjection of zinc-finger nucleases

Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

RNA-guided genetic silencing systems in bacteria and archaea

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

Transgenic swine for biomedicine and agriculture.

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10.1038/CR.2014.11

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3

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24

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