One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
about
Large animal models of cardiovascular diseaseGene targeting, genome editing: from Dolly to editorsCRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseasesClassification and evolution of type II CRISPR-Cas systemsOff-target Effects in CRISPR/Cas9-mediated Genome EngineeringCurrent progress of genetically engineered pig models for biomedical researchEfficient Generation of Myostatin Knock-Out Sheep Using CRISPR/Cas9 Technology and Microinjection into ZygotesPerspectives on avian stem cells for poultry breedingUse of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryosHighly efficient CRISPR/Cas9-mediated transgene knockin at the H11 locus in pigsHighly efficient generation of biallelic reporter gene knock-in mice via CRISPR-mediated genome editing of ESCsEfficient and versatile CRISPR engineering of human neurons in culture to model neurological disordersA CRISPR toolbox to study virus-host interactionsGenerating Mouse Models Using CRISPR-Cas9-Mediated Genome Editing.Cellular function reinstitution of offspring red blood cells cloned from the sickle cell disease patient blood post CRISPR genome editingGenetically modified pig models for neurodegenerative disorders.Myostatin gene knockout mediated by Cas9-D10A nickase in chicken DF1 cells without off-target effect.Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts.Myotube differentiation in clustered regularly interspaced short palindromic repeat/Cas9-mediated MyoD knockout quail myoblast cells.Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting.CRISPR/Cas9-mediated ApoE-/- and LDLR-/- double gene knockout in pigs elevates serum LDL-C and TC levels.The potential of the combination of CRISPR/Cas9 and pluripotent stem cells to provide human organs from chimaeric pigs.The production of multi-transgenic pigs: update and perspectives for xenotransplantation.An efficient genotyping method for genome-modified animals and human cells generated with CRISPR/Cas9 system.The meganuclease I-SceI containing nuclear localization signal (NLS-I-SceI) efficiently mediated mammalian germline transgenesis via embryo cytoplasmic microinjectionEfficient gene targeting in golden Syrian hamsters by the CRISPR/Cas9 system.A CRISPR view of development.Disruption of FGF5 in Cashmere Goats Using CRISPR/Cas9 Results in More Secondary Hair Follicles and Longer Fibers.Next-generation models of human cardiogenesis via genome editingEfficient generation of gene-modified pigs via injection of zygote with Cas9/sgRNA.CRISPR/Cas9 as tool for functional study of genes involved in preimplantation embryo development.Targeted Germline Modifications in Rats Using CRISPR/Cas9 and Spermatogonial Stem CellsEfficient gene knockout in goats using CRISPR/Cas9 system.Rosa26 locus supports tissue-specific promoter driving transgene expression specifically in pig.Review on porcine endogenous retrovirus detection assays--impact on quality and safety of xenotransplantsCloning-free CRISPR/Cas system facilitates functional cassette knock-in in mice.piRNAs from Pig Testis Provide Evidence for a Conserved Role of the Piwi Pathway in Post-Transcriptional Gene Regulation in Mammals.Brains, genes, and primates.Potential of promotion of alleles by genome editing to improve quantitative traits in livestock breeding programs.Eliminate mitochondrial diseases by gene editing in germ-line cells and embryos.
P2860
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P2860
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
2014年论文
@zh
2014年论文
@zh-cn
name
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
@en
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
@nl
type
label
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
@en
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
@nl
prefLabel
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
@en
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
@nl
P2093
P2860
P356
P1433
P1476
One-step generation of knockout pigs by zygote injection of CRISPR/Cas system.
@en
P2093
P2860
P2888
P304
P356
10.1038/CR.2014.11
P577
2014-01-31T00:00:00Z
P5875
P6179
1040674875