Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells.
about
G(i)-dependent localization of beta(2)-adrenergic receptor signaling to L-type Ca(2+) channelsA recombinant inwardly rectifying potassium channel coupled to GTP-binding proteinsMuscarinic K+ channel in the heart. Modal regulation by G protein beta gamma subunitsExpansion of signal transduction by G proteins. The second 15 years or so: from 3 to 16 alpha subunits plus betagamma dimersX-ray structure of the mammalian GIRK2–βγ G-protein complexGlycosylation of GIRK1 at Asn119 and ROMK1 at Asn117 has different consequences in potassium channel functionNumber and stoichiometry of subunits in the native atrial G-protein-gated K+ channel, IKAChInitial localization of regulatory regions of the cardiac sarcolemmal Na(+)-Ca2+ exchangerInhibition of acetylcholine-activated K(+) currents by U73122 is mediated by the inhibition of PIP(2)-channel interactionDistribution of the muscarinic K+ channel proteins Kir3.1 and Kir3.4 in the ventricle, atrium, and sinoatrial node of heartCombining pharmacology and whole-cell patch recording from CNS neurons, in vivo.Mass spectrometric analysis reveals a functionally important PKA phosphorylation site in a Kir3 channel subunitPotassium translocation by the Na+/K+ pump is voltage insensitiveSingle potassium channels opened by opioids in rat locus ceruleus neurons.G-protein mediated gating of inward-rectifier K+ channels.Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system.Low mobility of phosphatidylinositol 4,5-bisphosphate underlies receptor specificity of Gq-mediated ion channel regulation in atrial myocytes.Stimulation of cardiac alpha receptors increases Na/K pump current and decreases gK via a pertussis toxin-sensitive pathwayCalculation of time constants for intracellular diffusion in whole cell patch clamp configurationAntagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins.Mu and delta receptors belong to a family of receptors that are coupled to potassium channels.G protein coupling of receptors to ionic channels and other effector systems.Acetylcholine increases voltage-activated Ca2+ current in freshly dissociated smooth muscle cells.Emerging roles for G protein-gated inwardly rectifying potassium (GIRK) channels in health and disease.Agonist unbinding from receptor dictates the nature of deactivation kinetics of G protein-gated K+ channelsRegulation of the muscarinic K+ channel by extracellular ATP through membrane phosphatidylinositol 4,5-bisphosphate in guinea-pig atrial myocytesGd3+ and calcium sensitive, sodium leak currents are features of weak membrane-glass seals in patch clamp recordingsRegulation of the gating of cystic fibrosis transmembrane conductance regulator C1 channels by phosphorylation and ATP hydrolysisG protein-coupled receptor signaling to Kir channels in Xenopus oocytes.Muscarinic inhibition of nicotinic transmission in rat sympathetic neurons and adrenal chromaffin cells.Hypercholesterolemia induces up-regulation of KACh cardiac currents via a mechanism independent of phosphatidylinositol 4,5-bisphosphate and GβγActivation of the atrial KACh channel by the betagamma subunits of G proteins or intracellular Na+ ions depends on the presence of phosphatidylinositol phosphates.Modulation of brain Na+ channels by a G-protein-coupled pathwayTargeted inactivation of alphai2 or alphai3 disrupts activation of the cardiac muscarinic K+ channel, IK+Ach, in intact cells.Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K+ channelsMechanism of muscarinic receptor-induced K+ channel activation as revealed by hydrolysis-resistant GTP analoguesSodium-calcium exchange current. Dependence on internal Ca and Na and competitive binding of external Na and Ca.The nature and origin of spontaneous noise in G protein-gated ion channels.Functionally distinct phospho-forms underlie incremental activation of protein kinase-regulated Cl- conductance in mammalian heart.A G protein-gated K channel is activated via beta 2-adrenergic receptors and G beta gamma subunits in Xenopus oocytes.
P2860
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P2860
Mode of regulation of the ACh-sensitive K-channel by the muscarinic receptor in rabbit atrial cells.
description
1984 nî lūn-bûn
@nan
1984年の論文
@ja
1984年論文
@yue
1984年論文
@zh-hant
1984年論文
@zh-hk
1984年論文
@zh-mo
1984年論文
@zh-tw
1984年论文
@wuu
1984年论文
@zh
1984年论文
@zh-cn
name
Mode of regulation of the ACh- ...... ceptor in rabbit atrial cells.
@en
Mode of regulation of the ACh- ...... ceptor in rabbit atrial cells.
@nl
type
label
Mode of regulation of the ACh- ...... ceptor in rabbit atrial cells.
@en
Mode of regulation of the ACh- ...... ceptor in rabbit atrial cells.
@nl
prefLabel
Mode of regulation of the ACh- ...... ceptor in rabbit atrial cells.
@en
Mode of regulation of the ACh- ...... ceptor in rabbit atrial cells.
@nl
P356
P1433
P1476
Mode of regulation of the ACh- ...... ceptor in rabbit atrial cells.
@en
P2093
P2888
P304
P356
10.1007/BF00587544
P577
1984-04-01T00:00:00Z