Ddb1 is required for the proteolysis of the Schizosaccharomyces pombe replication inhibitor Spd1 during S phase and after DNA damage.
about
What is the functional role of the thalidomide binding protein cereblon?A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machineryNuclear localization of the Saccharomyces cerevisiae ribonucleotide reductase small subunit requires a karyopherin and a WD40 repeat protein.Rtt101 and Mms1 in budding yeast form a CUL4(DDB1)-like ubiquitin ligase that promotes replication through damaged DNAThe Schizosaccharomyces pombe replication inhibitor Spd1 regulates ribonucleotide reductase activity and dNTPs by binding to the large Cdc22 subunitDDB1 maintains genome integrity through regulation of Cdt1Functional characterization of the putative Aspergillus nidulans DNA damage binding protein homologue DdbA.Dif1 controls subcellular localization of ribonucleotide reductase by mediating nuclear import of the R2 subunitHepatitis B virus X protein stimulates viral genome replication via a DDB1-dependent pathway distinct from that leading to cell death.Composition and assembly of STAT-targeting ubiquitin ligase complexes: paramyxovirus V protein carboxyl terminus is an oligomerization domain.A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeastCul4A and DDB1 associate with Skp2 to target p27Kip1 for proteolysis involving the COP9 signalosomeThe Clr7 and Clr8 directionality factors and the Pcu4 cullin mediate heterochromatin formation in the fission yeast Schizosaccharomyces pombeCotransport of the heterodimeric small subunit of the Saccharomyces cerevisiae ribonucleotide reductase between the nucleus and the cytoplasmMechanism of immunomodulatory drugs' action in the treatment of multiple myeloma.Genetic Interaction Landscape Reveals Critical Requirements for Schizosaccharomyces pombe Brc1 in DNA Damage Response MutantsLoss of DDB1 Leads to Transcriptional p53 Pathway Activation in Proliferating Cells, Cell Cycle Deregulation, and Apoptosis in Zebrafish Embryos.The Cul4-Ddb1(Cdt)² ubiquitin ligase inhibits invasion of a boundary-associated antisilencing factor into heterochromatinA mutation in the tomato DDB1 gene affects cell and chloroplast compartment size and CDT1 transcriptProliferation defects and genome instability in cells lacking Cul4A.Spd1 accumulation causes genome instability independently of ribonucleotide reductase activity but functions to protect the genome when deoxynucleotide pools are elevated.CRL4s: the CUL4-RING E3 ubiquitin ligases.S-phase checkpoint regulations that preserve replication and chromosome integrity upon dNTP depletion.Schizosaccharomyces pombe Ddb1 recruits substrate-specific adaptor proteins through a novel protein motif, the DDB-box.The COP9 signalosome regulates Skp2 levels and proliferation of human cells.Break-induced ATR and Ddb1-Cul4(Cdt)² ubiquitin ligase-dependent nucleotide synthesis promotes homologous recombination repair in fission yeast.Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complexOrc2 protects ORCA from ubiquitin-mediated degradation.Ddb1 controls genome stability and meiosis in fission yeast.
P2860
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P2860
Ddb1 is required for the proteolysis of the Schizosaccharomyces pombe replication inhibitor Spd1 during S phase and after DNA damage.
description
2003 nî lūn-bûn
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2003年の論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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2003年論文
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name
Ddb1 is required for the prote ...... S phase and after DNA damage.
@en
Ddb1 is required for the prote ...... S phase and after DNA damage.
@nl
type
label
Ddb1 is required for the prote ...... S phase and after DNA damage.
@en
Ddb1 is required for the prote ...... S phase and after DNA damage.
@nl
prefLabel
Ddb1 is required for the prote ...... S phase and after DNA damage.
@en
Ddb1 is required for the prote ...... S phase and after DNA damage.
@nl
P2860
P356
P1476
Ddb1 is required for the prote ...... g S phase and after DNA damage
@en
P2093
Aleksandr Ponomarev
Pradip Raychaudhuri
P2860
P304
P356
10.1074/JBC.M312570200
P407
P50
P577
2003-12-29T00:00:00Z