APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease.
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Neuroprotective and disease-modifying effects of the ketogenic dietAuthors' ReplyA ketogenic diet reduces amyloid beta 40 and 42 in a mouse model of Alzheimer's disease.The Guinea Pig as a Model for Sporadic Alzheimer's Disease (AD): The Impact of Cholesterol Intake on Expression of AD-Related GenesAge-related loss of phospholipid asymmetry in APP(NLh)/APP(NLh) x PS-1(P264L)/PS-1(P264L) human double mutant knock-in mice: relevance to Alzheimer disease.Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma.Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice.Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.Autophagy dysfunction upregulates beta-amyloid peptides via enhancing the activity of γ-secretase complex.APP overexpression in the absence of NPC1 exacerbates metabolism of amyloidogenic proteins of Alzheimer's disease.Regulation of beta-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer's diseaseProtective Effect of Genistein against Neuronal Degeneration in ApoE-/- Mice Fed a High-Fat Diet.The role of cholesterol metabolism in Alzheimer's disease.Statins reduce amyloid-beta production through inhibition of protein isoprenylation.Effect of Metal Chelators on γ-Secretase Indicates That Calcium and Magnesium Ions Facilitate Cleavage of Alzheimer Amyloid Precursor Substrate.The effect of exogenous cholesterol and lipid-modulating agents on enterocytic amyloid-beta abundance.X-linked adrenoleukodystrophy mice demonstrate abnormalities in cholesterol metabolism.Effects of cholesterol transport inhibitor U18666A on APP metabolism in rat primary astrocytes.Elevated plasma cholesterol does not affect brain Abeta in mice lacking the low-density lipoprotein receptor.Atorvastatin and pitavastatin reduce oxidative stress and improve IR/LDL-R signals in Alzheimer's disease.Effects of diet-induced hypercholesterolemia on amyloid accumulation in ovariectomized mice.Chronic exposure to U18666A is associated with oxidative stress in cultured murine cortical neurons.Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content.
P2860
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P2860
APP intracellular domain is increased and soluble Abeta is reduced with diet-induced hypercholesterolemia in a transgenic mouse model of Alzheimer disease.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
APP intracellular domain is in ...... se model of Alzheimer disease.
@en
APP intracellular domain is in ...... se model of Alzheimer disease.
@nl
type
label
APP intracellular domain is in ...... se model of Alzheimer disease.
@en
APP intracellular domain is in ...... se model of Alzheimer disease.
@nl
prefLabel
APP intracellular domain is in ...... se model of Alzheimer disease.
@en
APP intracellular domain is in ...... se model of Alzheimer disease.
@nl
P2093
P50
P1476
APP intracellular domain is in ...... se model of Alzheimer disease.
@en
P2093
Catriona A McLean
Genevieve Evin
Katrina M Laughton
Qiao-Xin Li
R M Damian Holsinger
P304
P356
10.1016/J.NBD.2004.01.009
P577
2004-06-01T00:00:00Z