Huntington's disease gene (IT15) is widely expressed in human and rat tissues.
about
A novel X-linked gene, DDP, shows mutations in families with deafness (DFN-1), dystonia, mental deficiency and blindnessExpression and protein-binding studies of the EEN gene family, new interacting partners for dynamin, synaptojanin and huntingtin proteinsMolecular cloning of a full-length cDNA for dentatorubral-pallidoluysian atrophy and regional expressions of the expanded alleles in the CNSHuman induced pluripotent stem cells for monogenic disease modelling and therapyAbnormal kalirin signaling in neuropsychiatric disorders.Genetics and neuropathology of Huntington's diseaseHDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophyHydrophobically Modified siRNAs Silence Huntingtin mRNA in Primary Neurons and Mouse BrainPositional cloning of a gene involved in the pathogenesis of Treacher Collins syndrome. The Treacher Collins Syndrome Collaborative GroupRole of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesisCellular localization of the Huntington's disease protein and discrimination of the normal and mutated formCellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic miceMotivational, proteostatic and transcriptional deficits precede synapse loss, gliosis and neurodegeneration in the B6.HttQ111/+ model of Huntington's disease.Monkey hybrid stem cells develop cellular features of Huntington's disease.Age-associated chromatin relaxation is enhanced in Huntington's disease mice.Ubiquitin-activating enzyme activity contributes to differential accumulation of mutant huntingtin in brain and peripheral tissuesMicroglial Activation in the Pathogenesis of Huntington's Disease.Striatal Vulnerability in Huntington's Disease: Neuroprotection Versus Neurotoxicity.Body composition in premanifest Huntington's disease reveals lower bone density compared to controlsIdentification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodiesDifferential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.A recurrent expansion of a maternal allele with 36 CAG repeats causes Huntington disease in two sistersThe Huntington's disease-related cardiomyopathy prevents a hypertrophic response in the R6/2 mouse model.Preclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned?Transcription elongation and tissue-specific somatic CAG instability.A cellular perspective on conformational disease: the role of genetic background and proteostasis networks.Role of inositol 1,4,5-trisphosphate receptors in pathogenesis of Huntington's disease and spinocerebellar ataxiasStriatal pre-enkephalin overexpression improves Huntington's disease symptoms in the R6/2 mouse model of Huntington's diseaseDysfunction of the CNS-heart axis in mouse models of Huntington's disease.Three Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes.Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease miceMutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington's Disease T Lymphocytes.Characterization of Gastric Mucosa Biopsies Reveals Alterations in Huntington's Disease.CAG trinucleotide RNA repeats interact with RNA-binding proteins.White Adipose Tissue Browning in the R6/2 Mouse Model of Huntington's Disease.Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.Rho Kinase Pathway Alterations in the Brain and Leukocytes in Huntington's Disease.Huntington's Disease Protein Huntingtin Associates with its own mRNA.Cannabinoid receptor 2 signaling in peripheral immune cells modulates disease onset and severity in mouse models of Huntington's disease.Impaired regulation of brain mitochondria by extramitochondrial Ca2+ in transgenic Huntington disease rats
P2860
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P2860
Huntington's disease gene (IT15) is widely expressed in human and rat tissues.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Huntington's disease gene (IT15) is widely expressed in human and rat tissues.
@en
Huntington's disease gene
@nl
type
label
Huntington's disease gene (IT15) is widely expressed in human and rat tissues.
@en
Huntington's disease gene
@nl
prefLabel
Huntington's disease gene (IT15) is widely expressed in human and rat tissues.
@en
Huntington's disease gene
@nl
P2093
P1433
P1476
Huntington's disease gene (IT15) is widely expressed in human and rat tissues.
@en
P2093
Margolis RL
Schilling G
Wagster MV
Young WS 3rd
P304
P356
10.1016/0896-6273(93)90127-D
P407
P577
1993-11-01T00:00:00Z