Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer.
about
Transforming growth factor beta engages TACE and ErbB3 to activate phosphatidylinositol-3 kinase/Akt in ErbB2-overexpressing breast cancer and desensitizes cells to trastuzumabCancer Hallmarks, Biomarkers and Breast Cancer Molecular SubtypesErbB polymorphisms: insights and implications for response to targeted cancer therapeuticsClonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- VinorelbineSupervised risk predictor of breast cancer based on intrinsic subtypesIntrinsic resistance of tumorigenic breast cancer cells to chemotherapyTowards improved cancer diagnosis and prognosis using analysis of gene expression data and computer aided imaging.Structural similarity assessment for drug sensitivity prediction in cancer.ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics.Immune Signatures Following Single Dose Trastuzumab Predict Pathologic Response to PreoperativeTrastuzumab and Chemotherapy in HER2-Positive Early Breast Cancer.Personalizing HER2-targeted therapy in metastatic breast cancer beyond HER2 status: what we have learned from clinical specimensMultiplexed assessment of the Southwest Oncology Group-directed Intergroup Breast Cancer Trial S9313 by AQUA shows that both high and low levels of HER2 are associated with poor outcomeDNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response.Hydrophobic Fractionation Enhances Novel Protein Detection by Mass Spectrometry in Triple Negative Breast Cancer.Hydrophobic Proteome Analysis of Triple Negative and Hormone-Receptor-Positive-Her2-Negative Breast Cancer by Mass Spectrometer.Optical fiber-based in vivo quantification of growth factor receptors.Current status of anti-human epidermal growth factor receptor 2 therapies: predicting and overcoming herceptin resistanceBasal-like phenotype in a breast carcinoma case series from Sudan: prevalence and clinical/pathological correlations.Primary trastuzumab resistance: new tricks for an old drug.Identification of novel determinants of resistance to lapatinib in ERBB2-amplified cancers.Personalized drug combinations to overcome trastuzumab resistance in HER2-positive breast cancer.Evaluation of the anti-HER2 C6.5 diabody as a PET radiotracer to monitor HER2 status and predict response to trastuzumab treatmentInsulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1.The Functional Crosstalk between HER2 Tyrosine Kinase and TGF-β Signaling in Breast Cancer Malignancy.Upregulation of IGF-1R expression during neoadjuvant therapy predicts poor outcome in breast cancer patients.Role of IGF1R in Breast Cancer Subtypes, Stemness, and Lineage DifferentiationCD47-signal regulatory protein-α (SIRPα) interactions form a barrier for antibody-mediated tumor cell destruction.Invasive Breast Cancer: Recognition of Molecular SubtypesCytokeratin 5/6 fingerprinting in HER2-positive tumors identifies a poor prognosis and trastuzumab-resistant basal-HER2 subtype of breast cancer.Efficacy of neoadjuvant therapy with trastuzumab concurrent with anthracycline- and nonanthracycline-based regimens for HER2-positive breast cancer.Pharmacological strategies to overcome HER2 cross-talk and Trastuzumab resistance.Loss of human epidermal growth factor receptor 2 (HER2) expression in metastatic sites of HER2-overexpressing primary breast tumors.Genetic characterization of breast cancer and implications for clinical managementIncreased signalling of EGFR and IGF1R, and deregulation of PTEN/PI3K/Akt pathway are related with trastuzumab resistance in HER2 breast carcinomas.Intrinsic and acquired resistance to HER2-targeted therapies in HER2 gene-amplified breast cancer: mechanisms and clinical implicationsWhen tumor suppressor TGFβ meets the HER2 (ERBB2) oncogene.Deciphering the role of insulin-like growth factor-I receptor in trastuzumab resistance.Basal Protein Expression Is Associated With Worse Outcome and Trastuzamab Resistance in HER2+ Invasive Breast Cancer.Resistance to Trastuzumab in Breast Cancer.Molecular Mechanisms of Trastuzumab-Based Treatment in HER2-Overexpressing Breast Cancer
P2860
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P2860
Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Predictors of resistance to pr ...... -positive early breast cancer.
@en
Predictors of resistance to pr ...... -positive early breast cancer.
@nl
type
label
Predictors of resistance to pr ...... -positive early breast cancer.
@en
Predictors of resistance to pr ...... -positive early breast cancer.
@nl
prefLabel
Predictors of resistance to pr ...... -positive early breast cancer.
@en
Predictors of resistance to pr ...... -positive early breast cancer.
@nl
P2093
P1476
Predictors of resistance to pr ...... -positive early breast cancer.
@en
P2093
Agnes Witkiewicz
Beth-Ann Lesnikoski
Dennis Sgroi
Eric P Winer
Fanglei You
Harold J Burstein
J Dirk Iglehart
Lyndsay N Harris
Madhavi Kamma
Paula D Ryan
P304
P356
10.1158/1078-0432.CCR-06-1304
P407
P577
2007-02-01T00:00:00Z