beta -Amyloid peptide activates alpha 7 nicotinic acetylcholine receptors expressed in Xenopus oocytes.
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Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networksAllosteric modulator Desformylflustrabromine relieves the inhibition of α2β2 and α4β2 nicotinic acetylcholine receptors by β-amyloid(1-42) peptideMammalian nicotinic acetylcholine receptors: from structure to functionAmyloidosis in Retinal Neurodegenerative DiseasesDrug Development in Alzheimer's Disease: The Contribution of PET and SPECTα7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimumNicotinic ACh receptors as therapeutic targets in CNS disordersLoss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease.Cortical alpha7 nicotinic acetylcholine receptor and beta-amyloid levels in early Alzheimer disease.Positron emission tomography imaging and clinical progression in relation to molecular pathology in the first Pittsburgh Compound B positron emission tomography patient with Alzheimer's diseaseAmyloid beta from axons and dendrites reduces local spine number and plasticity.Peptide blockers of the inhibition of neuronal nicotinic acetylcholine receptors by amyloid beta.Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.A novel nicotinic acetylcholine receptor subtype in basal forebrain cholinergic neurons with high sensitivity to amyloid peptidesChronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease.Picomolar amyloid-β peptides enhance spontaneous astrocyte calcium transientsEndogenous signaling through alpha7-containing nicotinic receptors promotes maturation and integration of adult-born neurons in the hippocampus.Dual effect of beta-amyloid on α7 and α4β2 nicotinic receptors controlling the release of glutamate, aspartate and GABA in rat hippocampus.Functional α7β2 nicotinic acetylcholine receptors expressed in hippocampal interneurons exhibit high sensitivity to pathological level of amyloid β peptides.SSR180711, a novel selective alpha7 nicotinic receptor partial agonist: (1) binding and functional profile.Additive toxicity of β-amyloid by a novel bioactive peptide in vitro: possible implications for Alzheimer's disease.Amyloid-β as a modulator of synaptic plasticityRescue of amyloid-Beta-induced inhibition of nicotinic acetylcholine receptors by a peptide homologous to the nicotine binding domain of the alpha 7 subtype.α7 Nicotinic receptor-mediated astrocytic gliotransmitter release: Aβ effects in a preclinical Alzheimer's mouse model.Subtype-specific actions of beta-amyloid peptides on recombinant human neuronal nicotinic acetylcholine receptors (alpha7, alpha4beta2, alpha3beta4) expressed in Xenopus laevis oocytes.Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice.The keystone of Alzheimer pathogenesis might be sought in Aβ physiologyHippocampal Injections of Oligomeric Amyloid β-peptide (1-42) Induce Selective Working Memory Deficits and Long-lasting Alterations of ERK Signaling Pathway.Neuronal nicotinic acetylcholine receptors serve as sensitive targets that mediate beta-amyloid neurotoxicity.Specific mechanism for blood inflow stimulation in brain area prone to Alzheimer's disease lesions.Amyloid-β peptide: Dr. Jekyll or Mr. Hyde?Noncholinesterase effects induced by organophosphate pesticides and their relationship to cognitive processes: implication for the action of acylpeptide hydrolase.Non-hydrolytic functions of acetylcholinesterase. The significance of C-terminal peptides.Inhibition of native and recombinant nicotinic acetylcholine receptors by the myristoylated alanine-rich C kinase substrate peptide.Neurotransmitter receptor and time dependence of the synaptic plasticity disrupting actions of Alzheimer's disease Aβ in vivo.A novel nicotinic mechanism underlies β-amyloid-induced neuronal hyperexcitation.Neuronal nicotinic acetylcholine receptor-cholesterol crosstalk in Alzheimer's disease.Neuronal receptors as targets for the action of amyloid-beta protein (Aβ) in the brain.Neurotoxicity of amyloid β-protein: synaptic and network dysfunction.
P2860
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P2860
beta -Amyloid peptide activates alpha 7 nicotinic acetylcholine receptors expressed in Xenopus oocytes.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
beta -Amyloid peptide activate ...... expressed in Xenopus oocytes.
@en
beta -Amyloid peptide activate ...... expressed in Xenopus oocytes.
@nl
type
label
beta -Amyloid peptide activate ...... expressed in Xenopus oocytes.
@en
beta -Amyloid peptide activate ...... expressed in Xenopus oocytes.
@nl
prefLabel
beta -Amyloid peptide activate ...... expressed in Xenopus oocytes.
@en
beta -Amyloid peptide activate ...... expressed in Xenopus oocytes.
@nl
P2093
P2860
P356
P1476
beta -Amyloid peptide activate ...... expressed in Xenopus oocytes.
@en
P2093
J David Sweatt
Karen A Bell
Kelly T Dineley
P2860
P304
25056-25061
P356
10.1074/JBC.M200066200
P407
P577
2002-04-30T00:00:00Z