Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors.
about
Platelet signalingGpr126 functions in Schwann cells to control differentiation and myelination via G-protein activationTherapeutic approaches in arterial thrombosisDiscovering anti-platelet drug combinations with an integrated model of activator-inhibitor relationships, activator-activator synergies and inhibitor-inhibitor synergiesRGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injuryHierarchical organization in the hemostatic response and its relationship to the platelet-signaling network.Gαz regulates BDNF-induction of axon growth in cortical neurons.Implications of non-canonical G-protein signaling for the immune systemUnderstanding the role of prostaglandin E2 in regulating human platelet activity in health and diseaseThe loss of Gnai2 and Gnai3 in B cells eliminates B lymphocyte compartments and leads to a hyper-IgM like syndrome.Use of next-generation sequencing and candidate gene analysis to identify underlying defects in patients with inherited platelet function disorders.Clopidogrel: interactions with the P2Y12 receptor and clinical relevance.Platelet Gi protein Gαi2 is an essential mediator of thrombo-inflammatory organ damage in mice.An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver.Activation of microglial P2Y12 receptor is required for outward potassium currents in response to neuronal injury.Deletion of GαZ protein protects against diet-induced glucose intolerance via expansion of β-cell massPistacia chinensis Methanolic Extract Attenuated MAPK and Akt Phosphorylations in ADP Stimulated Rat Platelets In VitroPlatelets in atherothrombosis: lessons from mouse models.Live imaging of extracellular signal-regulated kinase and protein kinase A activities during thrombus formation in mice expressing biosensors based on Förster resonance energy transfer.Development of the mammalian axial skeleton requires signaling through the Gα(i) subfamily of heterotrimeric G proteins.Systems biology of platelet-vessel wall interactions.Platelet physiology and antiplatelet agents.Regulating thrombus growth and stability to achieve an optimal response to injury.Novel roles of cAMP/cGMP-dependent signaling in platelets.P2Y12 receptor: platelet thrombus formation and medical interventions.Platelet biology and receptor pathways.Harnessing the platelet signaling network to produce an optimal hemostatic response.P2 receptors and platelet function.Historical perspective on ADP-induced platelet activation.The P2X1 receptor and platelet function.New Concepts and Mechanisms of Platelet Activation Signaling.Intermolecular cross-talk between the prostaglandin E2 receptor (EP)3 of subtype and thromboxane A(2) receptor signalling in human erythroleukaemic cells.Gnaz couples the circadian and dopaminergic system to G protein-mediated signaling in mouse photoreceptors.Unresponsiveness of platelets lacking both Galpha(q) and Galpha(13). Implications for collagen-induced platelet activation.Role of G protein signaling in the formation of the fibrin(ogen)-integrin αIIbβ3-actin cytoskeleton complex in platelets.Role of P2Y12 Receptor in Thrombosis.Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets.RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists
P2860
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P2860
Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Signaling through Gi family me ...... l cyclase and other effectors.
@en
Signaling through Gi family me ...... l cyclase and other effectors.
@nl
type
label
Signaling through Gi family me ...... l cyclase and other effectors.
@en
Signaling through Gi family me ...... l cyclase and other effectors.
@nl
prefLabel
Signaling through Gi family me ...... l cyclase and other effectors.
@en
Signaling through Gi family me ...... l cyclase and other effectors.
@nl
P2093
P356
P1476
Signaling through Gi family me ...... l cyclase and other effectors.
@en
P2093
David R Manning
Donna Woulfe
Hong Jiang
Lawrence F Brass
Richard Mortensen
Sandra Austin
P304
46035-46042
P356
10.1074/JBC.M208519200
P407
P577
2002-09-23T00:00:00Z