Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats. - Wikidata - wikimedia - TriplyDB

Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats.

Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats.

http://www.wikidata.org/entity/Q42580171

about

The role of the serotonin receptor subtypes 5-HT1A and 5-HT7 and its interaction in emotional learning and memory Nicotinic α7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex Regulation of glutamate release by α7 nicotinic receptors: differential role in methamphetamine-induced damage to dopaminergic and serotonergic terminals nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives.Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia.Fluctuations in endogenous kynurenic acid control hippocampal glutamate and memory Thalamic glutamate decreases with cigarette smoking Targeting glutamate homeostasis for potential treatment of nicotine dependence.A systemically-available kynurenine aminotransferase II (KAT II) inhibitor restores nicotine-evoked glutamatergic activity in the cortex of rats Effects of age and acute ethanol on glutamatergic neurotransmission in the medial prefrontal cortex of freely moving rats using enzyme-based microelectrode amperometry.Pharmacological Mechanisms of Cortical Enhancement Induced by the Repetitive Pairing of Visual/Cholinergic Stimulation.Impact of prefrontal cortex in nicotine-induced excitation of ventral tegmental area dopamine neurons in anesthetized rats Elevated levels of kynurenic acid during gestation produce neurochemical, morphological, and cognitive deficits in adulthood: implications for schizophrenia.Adolescent nicotine exposure transiently increases high-affinity nicotinic receptors and modulates inhibitory synaptic transmission in rat medial prefrontal cortex Acute elevations of brain kynurenic acid impair cognitive flexibility: normalization by the alpha7 positive modulator galantamine.The astrocyte-derived alpha7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex.Electrochemical techniques for subsecond neurotransmitter detection in live rodents.Kynurenines and Glutamate: Multiple Links and Therapeutic Implications.Effects of chronic inhalation of electronic cigarettes containing nicotine on glial glutamate transporters and α-7 nicotinic acetylcholine receptor in female CD-1 mice.Kynurenic Acid in Schizophrenia: A Systematic Review and Meta-analysis.Temporal Rewiring of Striatal Circuits Initiated by Nicotine.Pre-synaptic nicotinic receptors evoke endogenous glutamate and aspartate release from hippocampal synaptosomes by way of distinct coupling mechanisms.Integration of inhibitory and excitatory effects of α7 nicotinic acetylcholine receptor activation in the prelimbic cortex regulates network activity and plasticity.Cortical kynurenic acid bi-directionally modulates prefrontal glutamate levels as assessed by microdialysis and rapid electrochemistry.Soluble Amyloid-β42 Stimulates Glutamate Release through Activation of the α7 Nicotinic Acetylcholine Receptor.Prenatal kynurenine exposure in rats: age-dependent changes in NMDA receptor expression and conditioned fear responding.Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys.Requirement of α7 nicotinic acetylcholine receptors for amyloid β protein-induced depression of hippocampal long-term potentiation in CA1 region of rats in vivo.Oral administration of a specific kynurenic acid synthesis (KAT II) inhibitor attenuates evoked glutamate release in rat prefrontal cortex.Amperometric Self-Referencing Ceramic Based Microelectrode Arrays for D-Serine Detection.A computerized exposure system for animal models to optimize nicotine delivery into the brain through inhalation of electronic cigarette vapors or cigarette smoke.

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Second-by-second analysis of alpha 7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats.

http://www.wikidata.org/entity/Q42580171

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2009 nî lūn-bûn

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Asa Konradsson-Geuken

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Clelland R Gash

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Francois Pomerleau

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Greg A Gerhardt

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John P Bruno

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Kathleen Alexander

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Peter Huettl

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P2860

Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia

The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications

NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development

DL-threo-beta-benzyloxyaspartate, a potent blocker of excitatory amino acid transporters

Nicotinic acetylcholine involvement in cognitive function in animals

The comparative pharmacology and up-regulation of rat neuronal nicotinic receptor subtype binding sites stably expressed in transfected mammalian cells

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways

Nicotinic modulation of neuronal networks: from receptors to cognition.

Nicotinic receptors mediate the release of amino acid neurotransmitters in cultured cortical neurons.

Dysfunctional and compensatory prefrontal cortical systems, genes and the pathogenesis of schizophrenia.

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10.1002/SYN.20693

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12

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