Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats.
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Brivaracetam: a rational drug discovery success storyMonotherapy for partial epilepsy: focus on levetiracetamLevetiracetam in the treatment of epilepsyDiverse mechanisms of antiepileptic drugs in the development pipelineModern antiepileptic drug development has failed to deliver: ways out of the current dilemma.Synaptic Vesicle Glycoprotein 2A Ligands in the Treatment of Epilepsy and BeyondDeveloping novel antiepileptic drugs: characterization of NAX 5055, a systemically-active galanin analog, in epilepsy modelsA microdialysis study of the novel antiepileptic drug levetiracetam: extracellular pharmacokinetics and effect on taurine in rat brainZ944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling ModelThe anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currentsLevetiracetam and partial seizure subtypes: pooled data from three randomized, placebo-controlled trials.Levetiracetam: the profile of a novel anticonvulsant drug-part I: preclinical data.Levetiracetam attenuates hippocampal expression of synaptic plasticity-related immediate early and late response genes in amygdala-kindled ratsIntravenous levetiracetam in the rat pilocarpine-induced status epilepticus model: behavioral, physiological and histological studies.An assessment of levetiracetam as an anti-epileptic drug.Molecular targets versus models for new antiepileptic drug discoveryNew treatment options in status epilepticus: a critical review on intravenous levetiracetam.Levetiracetam: a novel antiepileptic drug.Validation of the zebrafish pentylenetetrazol seizure model: locomotor versus electrographic responses to antiepileptic drugs.Profile of anticonvulsant action of levetiracetam, tiagabine and phenobarbital against seizures evoked by DMCM (methyl-6,7-dimethoxy-4-ethyl-β-carboline-3-carboxylate) in neonatal rats.Emerging drugs for epilepsy.Asymmetric accumulation of hippocampal 7S SNARE complexes occurs regardless of kindling paradigm.Therapeutic drug monitoring of old and newer anti-epileptic drugs.Levetiracetam in pediatrics.Discovery of antiepileptic drugs.Levetiracetam Extended Release as Adjuvant Therapy for the Control of Partial-onset Seizures.Levetiracetam prevents kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes.Is levetiracetam different from other antiepileptic drugs? Levetiracetam and its cellular mechanism of action in epilepsy revisited.Brivaracetam: Rationale for discovery and preclinical profile of a selective SV2A ligand for epilepsy treatment.Antiepileptic Drug Discovery and Development: What Have We Learned and Where Are We Going?Antiepileptic drug discovery: lessons from the past and future challenges.ONO-2506 inhibits spike-wave discharges in a genetic animal model without affecting traditional convulsive tests via gliotransmission regulation.A comparison of the efficacy of carbamazepine and the novel anti-epileptic drug levetiracetam in the tetanus toxin model of focal complex partial epilepsyCharacterization of the anticonvulsant profile and enantioselective pharmacokinetics of the chiral valproylamide propylisopropyl acetamide in rodents.Levetiracetam: an innovative and cost-effective add-on drug for refractory partial epilepsy.Pharmacokinetics of levetiracetam and its enantiomer (R)-alpha-ethyl-2-oxo-pyrrolidine acetamide in dogs.Comparative pharmacokinetics and metabolism of levetiracetam, a new anti-epileptic agent, in mouse, rat, rabbit and dog.Synergism of lacosamide with established antiepileptic drugs in the 6-Hz seizure model in mice.Pharmacokinetics of the anti-convulsant levetiracetam in neonatal foals.Use of chronic epilepsy models in antiepileptic drug discovery: the effect of topiramate on spontaneous motor seizures in rats with kainate-induced epilepsy.
P2860
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P2860
Profile of ucb L059, a novel anticonvulsant drug, in models of partial and generalized epilepsy in mice and rats.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
1993年论文
@zh
1993年论文
@zh-cn
name
Profile of ucb L059, a novel a ...... zed epilepsy in mice and rats.
@en
Profile of ucb L059, a novel a ...... zed epilepsy in mice and rats.
@nl
type
label
Profile of ucb L059, a novel a ...... zed epilepsy in mice and rats.
@en
Profile of ucb L059, a novel a ...... zed epilepsy in mice and rats.
@nl
prefLabel
Profile of ucb L059, a novel a ...... zed epilepsy in mice and rats.
@en
Profile of ucb L059, a novel a ...... zed epilepsy in mice and rats.
@nl
P1476
Profile of ucb L059, a novel a ...... zed epilepsy in mice and rats.
@en
P2093
P304
P356
10.1016/0014-2999(93)90768-D
P407
P577
1993-03-01T00:00:00Z