Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants
about
Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteinsEffect of G protein heterotrimer composition on coupling of neurotransmitter receptors to N-type Ca(2+) channel modulation in sympathetic neuronsEndogenous regulators of G protein signaling proteins regulate presynaptic inhibition at rat hippocampal synapsesRegulators of G-protein signaling form a quaternary complex with the agonist, receptor, and G-protein. A novel explanation for the acceleration of signaling activation kinetics.Gi protein activation in intact cells involves subunit rearrangement rather than dissociationCoupling specificity of NOP opioid receptors to pertussis-toxin-sensitive Galpha proteins in adult rat stellate ganglion neurons using small interference RNAThe role of members of the pertussis toxin-sensitive family of G proteins in coupling receptors to the activation of the G protein-gated inwardly rectifying potassium channel.Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity.betagamma dimers derived from Go and Gi proteins contribute different components of adrenergic inhibition of Ca2+ channels in rat sympathetic neurones.Measurement of agonist-induced guanine nucleotide turnover by the G-protein Gi1alpha when constrained within an alpha2A-adrenoceptor-Gi1alpha fusion protein.Gating properties of GIRK channels activated by Galpha(o)- and Galpha(i)-coupled muscarinic m2 receptors in Xenopus oocytes: the role of receptor precoupling in RGS modulation.The human delta opioid receptor activates G(i1)alpha more efficiently than G(o1)alpha.Growth hormone secretagogues and growth hormone releasing peptides act as orthosteric super-agonists but not allosteric regulators for activation of the G protein Galpha(o1) by the Ghrelin receptor.Concerted stimulation and deactivation of pertussis toxin-sensitive G proteins by chimeric G protein-coupled receptor-regulator of G protein signaling 4 fusion proteins: analysis of the contribution of palmitoylated cysteine residues to the GAP actiAgonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently.A novel strategy to engineer functional fluorescent inhibitory G-protein alpha subunits.Agonist occupation of an alpha2A-adrenoreceptor-Gi1alpha fusion protein results in activation of both receptor-linked and endogenous Gi proteins. Comparisons of their contributions to GTPase activity and signal transduction and analysis of receptor-Ric-8A, an activator protein of Gαi, controls mammalian epithelial cell polarity for tight junction assembly and cystogenesis.Multiple pertussis toxin-sensitive G-proteins can couple receptors to GIRK channels in rat sympathetic neurons when expressed heterologously, but only native G(i)-proteins do so in situ.Potent biphalin analogs with µ/δ mixed opioid activity: in vivo and in vitro biological evaluation.Constitutively active Gq/11-coupled receptors enable signaling by co-expressed G(i/o)-coupled receptors.Quantitative analysis of a cysteine351glycine mutation in the G protein Gi1alpha: effect on alpha2A-adrenoceptor-Gi1alpha fusion protein activation.Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons.Rescue of functional interactions between the alpha2A-adrenoreceptor and acylation-resistant forms of Gi1alpha by expressing the proteins from chimeric open reading frames.Functional analysis of a human A(1) adenosine receptor/green fluorescent protein/G(i1)alpha fusion protein following stable expression in CHO cells.
P2860
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P2860
Interactions of the alpha2A-adrenoceptor with multiple Gi-family G-proteins: studies with pertussis toxin-resistant G-protein mutants
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Interactions of the alpha2A-ad ...... in-resistant G-protein mutants
@en
Interactions of the alpha2A-ad ...... in-resistant G-protein mutants
@nl
type
label
Interactions of the alpha2A-ad ...... in-resistant G-protein mutants
@en
Interactions of the alpha2A-ad ...... in-resistant G-protein mutants
@nl
prefLabel
Interactions of the alpha2A-ad ...... in-resistant G-protein mutants
@en
Interactions of the alpha2A-ad ...... in-resistant G-protein mutants
@nl
P2093
P2860
P356
P1433
P1476
Interactions of the alpha2A-ad ...... in-resistant G-protein mutants
@en
P2093
P2860
P304
P356
10.1042/BJ3210721
P407
P478
321 ( Pt 3)
P577
1997-02-01T00:00:00Z