Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor.
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Protein design: toward functional metalloenzymesRational design of a structural and functional nitric oxide reductaseNMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptorComputational Redesign of Thioredoxin Is Hypersensitive toward Minor Conformational Changes in the Backbone TemplateCollective dynamics differentiates functional divergence in protein evolutionEffects of Non-Natural Amino Acid Incorporation into the Enzyme Core Region on Enzyme Structure and Function.Computational approaches for rational design of proteins with novel functionalitiesComputational de novo design of a four-helix bundle protein--DND_4HB.The Framework of Computational Protein Design.Achievements and Challenges in Computational Protein Design.Designing artificial enzymes by intuition and computationAmphiphilic peptide-polymer conjugates with side-conjugation.Statistical theory for protein ensembles with designed energy landscapes.New design of helix bundle peptide-polymer conjugates.Structural principles for computational and de novo design of 4Fe-4S metalloproteins.Computational design of antibody-affinity improvement beyond in vivo maturationControlling and fine tuning the physical properties of two identical metal coordination sites in de novo designed three stranded coiled coil peptides.Computational design and elaboration of a de novo heterotetrameric alpha-helical protein that selectively binds an emissive abiological (porphinato)zinc chromophoreComputational protein design: engineering molecular diversity, nonnatural enzymes, nonbiological cofactor complexes, and membrane proteins.Computational design of membrane proteins.RosettaRemodel: a generalized framework for flexible backbone protein design.Design of functional metalloproteins.Design of a three-helix bundle capable of binding heavy metals in a triscysteine environment.Computational protein design: Advances in the design and redesign of biomolecular nanostructuresProton coupled electron transfer and redox active tyrosines in Photosystem IIFluorescence correlation spectroscopic study of serpin depolymerization by computationally designed peptides.Adding energy minimization strategy to peptide-design algorithm enables better search for RNA-binding peptides: Redesigned λ N peptide binds boxB RNA.Progress in computational protein design.Protein folding thermodynamics and dynamics: where physics, chemistry, and biology meet.First principles design of a core bioenergetic transmembrane electron-transfer protein.Using alpha-helical coiled-coils to design nanostructured metalloporphyrin arraysComputational de novo design and characterization of a protein that selectively binds a highly hyperpolarizable abiological chromophore.Recent progress toward the templated synthesis and directed evolution of sequence-defined synthetic polymersX-ray vs. NMR structures as templates for computational protein design.Challenges in the computational design of proteinsImproving computational efficiency and tractability of protein design using a piecemeal approach. A strategy for parallel and distributed protein design.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.De Novo Design of Xeno-Metallo Coiled Coils.Geometric constraints for porphyrin binding in helical protein binding sites.Functional and mechanistic analyses of biomimetic aminoacyl transfer reactions in de novo designed coiled coil peptides via rational active site engineering.
P2860
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P2860
Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Computational de novo design a ...... inds a nonbiological cofactor.
@en
Computational de novo design a ...... inds a nonbiological cofactor.
@nl
type
label
Computational de novo design a ...... inds a nonbiological cofactor.
@en
Computational de novo design a ...... inds a nonbiological cofactor.
@nl
prefLabel
Computational de novo design a ...... inds a nonbiological cofactor.
@en
Computational de novo design a ...... inds a nonbiological cofactor.
@nl
P2093
P50
P356
P1476
Computational de novo design a ...... inds a nonbiological cofactor.
@en
P2093
Frank V Cochran
Michael J Therien
Sophia P Wu
P304
P356
10.1021/JA044129A
P407
P577
2005-02-01T00:00:00Z