A microRNA-regulated and GP64-pseudotyped lentiviral vector mediates stable expression of FVIII in a murine model of Hemophilia A.
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MicroRNA-regulated viral vectors for gene therapyThe gene therapy journey for hemophilia: are we there yet?Animal models of hemophiliaMicroRNA in atherothromobosis: is it useful as a disease marker?Gene therapy for hemophiliaToward Personalized Gene Therapy: Characterizing the Host Genetic Control of Lentiviral-Vector-Mediated Hepatic Gene Delivery.In vivo enrichment of genetically manipulated platelets corrects the murine hemophilic phenotype and induces immune tolerance even using a low multiplicity of infectionExploiting microRNA regulation for genetic engineering.Inhibitors - cellular aspects and novel approaches for tolerance.Specific micro RNA-regulated TetR-KRAB transcriptional control of transgene expression in viral vector-transduced cells.piggyBac-mediated phenotypic correction of factor VIII deficiencyDelivery of full-length factor VIII using a piggyBac transposon vector to correct a mouse model of hemophilia A.Perinatal gene transfer to the liver.Gene therapy for haemophilia: prospects and challenges to prevent or reverse inhibitor formation.Manipulating Immune Tolerance with Micro-RNA Regulated Gene Therapy.Endothelial progenitor cell-based therapy for hemophilia A.Progress toward inducing immunologic tolerance to factor VIII.Current status of haemophilia gene therapy.New approaches to gene and cell therapy for hemophilia.Baboon envelope pseudotyped lentiviral vectors efficiently transduce human B cells and allow active factor IX B cell secretion in vivo in NOD/SCIDγc-/- mice.In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice.Retroviral and lentiviral vectors for the induction of immunological tolerance.A TLR and non-TLR mediated innate response to lentiviruses restricts hepatocyte entry and can be ameliorated by pharmacological blockade.Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy.Liver-directed lentiviral gene therapy in a dog model of hemophilia B.Hepatic lentiviral gene transfer prevents the long-term onset of hepatic tumours of glycogen storage disease type 1a in mice.Advances in Overcoming Immune Responses following Hemophilia Gene Therapy.Mir-142-3p target sequences reduce transgene-directed immunogenicity following intramuscular adeno-associated virus 1 vector-mediated gene delivery.A Novel Platform for Immune Tolerance Induction in Hemophilia A Mice.Immune tolerance induced by platelet-targeted factor VIII gene therapy in hemophilia A mice is CD4 T cell mediated.Gene Therapy for Hemophilia: Progress to Date.Innovative Approaches for Immune Tolerance to Factor VIII in the Treatment of Hemophilia A.Lessons learned from lung and liver in-vivo gene therapy: implications for the futurePlatelet Gene Therapy Promotes Targeted Peripheral Tolerance by Clonal Deletion and Induction of Antigen-Specific Regulatory T Cells
P2860
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P2860
A microRNA-regulated and GP64-pseudotyped lentiviral vector mediates stable expression of FVIII in a murine model of Hemophilia A.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
A microRNA-regulated and GP64- ...... murine model of Hemophilia A.
@en
A microRNA-regulated and GP64- ...... murine model of Hemophilia A.
@nl
type
label
A microRNA-regulated and GP64- ...... murine model of Hemophilia A.
@en
A microRNA-regulated and GP64- ...... murine model of Hemophilia A.
@nl
prefLabel
A microRNA-regulated and GP64- ...... murine model of Hemophilia A.
@en
A microRNA-regulated and GP64- ...... murine model of Hemophilia A.
@nl
P2093
P2860
P921
P356
P1433
P1476
A microRNA-regulated and GP64- ...... murine model of Hemophilia A.
@en
P2093
Andrea Labelle
Angie Tuttle
Brian Brown
Carol Hegadorn
Christine Hough
David Lillicrap
Erin Burnett
Hideto Matsui
Margareth Ozelo
P2860
P304
P356
10.1038/MT.2010.290
P577
2011-02-01T00:00:00Z