Melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 modified at the para position of the benzyl side chain (DPhe): importance for mouse melanocortin-3 receptor agonist versus antagonist activity.
about
Azepinone-Containing Tetrapeptide Analogues of Melanotropin Lead to Selective hMC4R Agonists and hMC5R AntagonistIdentification of tetrapeptides from a mixture based positional scanning library that can restore nM full agonist function of the L106P, I69T, I102S, A219V, C271Y, and C271R human melanocortin-4 polymorphic receptors (hMC4Rs).Discovery of Mixed Pharmacology Melanocortin-3 Agonists and Melanocortin-4 Receptor Tetrapeptide Antagonist Compounds (TACOs) Based on the Sequence Ac-Xaa1-Arg-(pI)DPhe-Xaa4-NH2.Bench-top to clinical therapies: A review of melanocortin ligands from 1954 to 2016.Pharmacological characterization of 30 human melanocortin-4 receptor polymorphisms with the endogenous proopiomelanocortin-derived agonists, synthetic agonists, and the endogenous agouti-related protein antagonist.Implication of the melanocortin-3 receptor in the regulation of food intake.Melanocortin antagonist tetrapeptides with minimal agonist activity at the mouse melanocortin-3 receptor.Synthesis and Structure-Activity Relationships of Substituted Urea Derivatives on Mouse Melanocortin Receptors.Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH2, leads to hMC1R selectivity and pigmentation.
P2860
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P2860
Melanocortin tetrapeptide Ac-His-DPhe-Arg-Trp-NH2 modified at the para position of the benzyl side chain (DPhe): importance for mouse melanocortin-3 receptor agonist versus antagonist activity.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Melanocortin tetrapeptide Ac-H ...... st versus antagonist activity.
@en
Melanocortin tetrapeptide Ac-H ...... ition of the benzyl side chain
@nl
type
label
Melanocortin tetrapeptide Ac-H ...... st versus antagonist activity.
@en
Melanocortin tetrapeptide Ac-H ...... ition of the benzyl side chain
@nl
prefLabel
Melanocortin tetrapeptide Ac-H ...... st versus antagonist activity.
@en
Melanocortin tetrapeptide Ac-H ...... ition of the benzyl side chain
@nl
P2093
P2860
P356
P1476
Melanocortin tetrapeptide Ac-H ...... st versus antagonist activity.
@en
P2093
Bettina Proneth
Carrie Haskell-Luevano
Federico P Portillo
Henry I Mosberg
Irina D Pogozheva
P2860
P304
P356
10.1021/JM800291B
P407
P577
2008-09-01T00:00:00Z