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ZIP kinase triggers apoptosis from nuclear PML oncogenic domainsIdentification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cellsRas-induced cellular events (review)Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cellsRAS oncogenes: weaving a tumorigenic webExpression and regulation of prostate apoptosis response-4 (Par-4) in human glioma stem cells in drug-induced apoptosisRegulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cellsRegulation of mature T lymphocyte proliferation and differentiation by Par-4The Ras effector RASSF2 controls the PAR-4 tumor suppressor.Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network.The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosisExpression and function of prostate-apoptosis-response-gene-4 in lymphatic cells.Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38Tumour-suppression activity of the proapoptotic regulator Par4.Suppression of PTEN expression by NF-kappa B prevents apoptosis.The dark side of Ras: regulation of apoptosis.Prostate apoptosis response 4 (Par-4), a novel substrate of caspase-3 during apoptosis activation.Clinical significance of GADD153 expression in stage I non-small cell lung cancer.Role of PAR-4 in ovarian cancer.Par-4 binds to topoisomerase 1 and attenuates its DNA relaxation activityChemoprevention of pancreatic cancer: characterization of Par-4 and its modulation by 3,3' diindolylmethane (DIM)Apoptosis and tumor resistance conferred by Par-4Post-translational regulation of the cleaved fragment of Par-4 in ovarian and endometrial cancer cells.Simultaneous dual targeting of Par-4 and G6PD: a promising new approach in cancer therapy? Quintessence of a literature review on survival requirements of tumor cells.The Par-4/PTEN connection in tumor suppression.Prostate apoptosis response-4 mediates TGF-β-induced epithelial-to-mesenchymal transition.PAR-4 as a possible new target for pancreatic cancer therapy.Cancer-selective apoptotic effects of extracellular and intracellular Par-4.Par-4 as a potential target for cancer therapy.pH-induced folding of an apoptotic coiled coil.A journey beyond apoptosis: new enigma of controlling metastasis by pro-apoptotic Par-4.Par-4 dependent modulation of cellular β-catenin by medicinal plant natural product derivative 3-azido Withaferin A.PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells.Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survivalIsolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers.Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.Genetic inactivation of Par4 results in hyperactivation of NF-kappaB and impairment of JNK and p38.Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.Phosphorylation of Par-4 by protein kinase A is critical for apoptosis.Oncogenic ras mediates apoptosis in response to protein kinase C inhibition through the generation of reactive oxygen species.
P2860
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P2860
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Oncogenic Ras sensitizes cells to apoptosis by Par-4.
@en
Oncogenic Ras sensitizes cells to apoptosis by Par-4.
@nl
type
label
Oncogenic Ras sensitizes cells to apoptosis by Par-4.
@en
Oncogenic Ras sensitizes cells to apoptosis by Par-4.
@nl
prefLabel
Oncogenic Ras sensitizes cells to apoptosis by Par-4.
@en
Oncogenic Ras sensitizes cells to apoptosis by Par-4.
@nl
P2093
P2860
P356
P1476
Oncogenic Ras sensitizes cells to apoptosis by Par-4.
@en
P2093
P2860
P304
29976-29983
P356
10.1074/JBC.274.42.29976
P407
P577
1999-10-01T00:00:00Z