Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38
about
Ras, an actor on many stages: posttranslational modifications, localization, and site-specified events.p38α MAPK pathway: a key factor in colorectal cancer therapy and chemoresistance.RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effectsIn TCR-stimulated T-cells, N-ras regulates specific genes and signal transduction pathwaysOncogenic Ras stimulates Eiger/TNF exocytosis to promote growth.RASSF7 negatively regulates pro-apoptotic JNK signaling by inhibiting the activity of phosphorylated-MKK7Classic Ras Proteins Promote Proliferation and Survival via Distinct Phosphoproteome Alterations in Neurofibromin-Null Malignant Peripheral Nerve Sheath Tumor Cells.Estradiol abrogates apoptosis in breast cancer cells through inactivation of BAD: Ras-dependent nongenomic pathways requiring signaling through ERK and AktWild-type NRas and KRas perform distinct functions during transformation.Expression of c-Jun, p73, Casp9, and N-ras in thymic epithelial tumors: relationship with the current WHO classification systems.RASSF7 expression and its regulatory roles on apoptosis in human intervertebral disc degeneration.Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progressionDifferential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.Antifouling surfaces for proteins labeled with dye-doped silica nanoparticlesIntegration of multiple signaling pathway activities resolves K-RAS/N-RAS mutation paradox in colon epithelial cell response to inflammatory cytokine stimulation.The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agentsBevacizumab-based treatment in colorectal cancer with a NRAS Q61K mutation.Reactive oxygen species: a double-edged sword in oncogenesis.H-Ras-specific activation of Rac-MKK3/6-p38 pathway: its critical role in invasion and migration of breast epithelial cells.p38 Mitogen-activated protein kinase signaling, ERCC1 expression, and viability of lung cancer cells from never or light smoker patients.Oncogenic K-RAS subverts the antiapoptotic role of N-RAS and alters modulation of the N-RAS:gelsolin complex.Transcriptional networks of knockout cell lines identify functional specificities of H-Ras and N-Ras: significant involvement of N-Ras in biotic and defense responses.Epidermal growth factor-stimulated intestinal epithelial cell migration requires Src family kinase-dependent p38 MAPK signaling.Basic fibroblast growth factor-induced cell death is effected through sustained activation of p38MAPK and up-regulation of the death receptor p75NTR.Dual effects of Ral-activated pathways on p27 localization and TGF-β signalingLoss of integrin alpha1beta1 ameliorates Kras-induced lung cancer.Pathway- and expression level-dependent effects of oncogenic N-Ras: p27(Kip1) mislocalization by the Ral-GEF pathway and Erk-mediated interference with Smad signalingSignaling through the TRAIL receptor DR5/FADD pathway plays a role in the apoptosis associated with skeletal myoblast differentiation.Functional specificity of ras isoforms: so similar but so different.Fabrication of carbohydrate microarrays on a poly(2-hydroxyethyl methacrylate)-based photoactive substrate.
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P2860
Cellular N-Ras promotes cell survival by downregulation of Jun N-terminal protein kinase and p38
description
2002 nî lūn-bûn
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2002 թուականի Մարտին հրատարակուած գիտական յօդուած
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2002 թվականի մարտին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@ast
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@en
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@nl
type
label
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@ast
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@en
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@nl
prefLabel
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@ast
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@en
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@nl
P2093
P2860
P1476
Cellular N-Ras promotes cell s ...... erminal protein kinase and p38
@en
P2093
Alan Wolfman
Channing J Der
Janice C Wolfman
Todd Palmby
P2860
P304
P356
10.1128/MCB.22.5.1589-1606.2002
P407
P577
2002-03-01T00:00:00Z