Requirement for c-ras proteins during viral oncogene transformation.
about
The complete coding sequence of the human A-raf-1 oncogene and transforming activity of a human A-raf carrying retrovirusIdentification of a mammalian gene structurally and functionally related to the CDC25 gene of Saccharomyces cerevisiae14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent mannerAsh/Grb-2, a SH2/SH3-containing protein, couples to signaling for mitogenesis and cytoskeletal reorganization by EGF and PDGFBcr-Abl oncoproteins bind directly to activators of the Ras signalling pathwayThe SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signallingIsolation of rsp-1, a novel cDNA capable of suppressing v-Ras transformationCharacterization of a novel member of the DOK family that binds and modulates Abl signalingActivation of extracellular signal-regulated kinase, ERK2, by p21ras oncoproteinp21ras activation via hemopoietin receptors and c-kit requires tyrosine kinase activity but not tyrosine phosphorylation of p21ras GTPase-activating proteinMolecular features of the viral and cellular Src kinases involved in interactions with the GTPase-activating protein.The Sos1 and Sos2 Ras-specific exchange factors: differences in placental expression and signaling propertiesTyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activationTyrosine phosphorylation of BCR by FPS/FES protein-tyrosine kinases induces association of BCR with GRB-2/SOSAssociation of p62, a multifunctional SH2- and SH3-domain-binding protein, with src family tyrosine kinases, Grb2, and phospholipase C gamma-1Targeting Protein Kinase C Downstream of Growth Factor and Adhesion SignallingThe hunting of the SrcB-raf oncogene: activation by rearrangements and assignment to human chromosome 7The Ras GTPase-activating protein (GAP) is an SH3 domain-binding protein and substrate for the Src-related tyrosine kinase, HckProtein farnesyltransferase inhibitors block the growth of ras-dependent tumors in nude miceThe cytostatic function of c-Abl is controlled by multiple nuclear localization signals and requires the p53 and Rb tumor suppressor gene productsGTPase-activating protein interactions with the viral and cellular Src kinases.Protein-tyrosine kinases regulate the phosphorylation, protein interactions, subcellular distribution, and activity of p21ras GTPase-activating proteinAssociation of MEK1 with p21ras.GMPPNP is dependent on B-Raf.Hepatic epidermal growth factor-regulated mitogen-activated protein kinase kinase kinase activity in the rat: lack of identity with known forms of raf and MEKKMutation of Tyr697, a GRB2-binding site, and Tyr721, a PI 3-kinase binding site, abrogates signal transduction by the murine CSF-1 receptor expressed in Rat-2 fibroblastsThe role of the Src homology domains in morphological transformation by v-srcActivation of the JNK pathway is essential for transformation by the Met oncogeneRequirement for the adapter protein GRB2 in EGF receptor endocytosis.IL-5 receptor-mediated tyrosine phosphorylation of SH2/SH3-containing proteins and activation of Bruton's tyrosine and Janus 2 kinases.Both the SH2 and SH3 domains of human CRK protein are required for neuronal differentiation of PC12 cells.BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemias.The role of SRC-CAS interactions in cellular transformation: ectopic expression of the carboxy terminus of CAS inhibits SRC-CAS interaction but has no effect on cellular transformation.Ras history: The saga continues.Mutational activation of c-raf-1 and definition of the minimal transforming sequence.Regulation of tetradecanoyl phorbol acetate-induced responses in NIH 3T3 cells by GAP, the GTPase-activating protein associated with p21c-ras.Transformation by pp60src or stimulation of cells with epidermal growth factor induces the stable association of tyrosine-phosphorylated cellular proteins with GTPase-activating protein.An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity.Interferons block protein kinase C-dependent but not-independent activation of Raf-1 and mitogen-activated protein kinases and mitogenesis in NIH 3T3 cells.Inhibition of v-src-induced transformation by a GTPase-activating protein
P2860
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P2860
Requirement for c-ras proteins during viral oncogene transformation.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
1986年论文
@zh
1986年论文
@zh-cn
name
Requirement for c-ras proteins during viral oncogene transformation.
@en
Requirement for c-ras proteins during viral oncogene transformation.
@nl
type
label
Requirement for c-ras proteins during viral oncogene transformation.
@en
Requirement for c-ras proteins during viral oncogene transformation.
@nl
prefLabel
Requirement for c-ras proteins during viral oncogene transformation.
@en
Requirement for c-ras proteins during viral oncogene transformation.
@nl
P2093
P356
P1433
P1476
Requirement for c-ras proteins during viral oncogene transformation.
@en
P2093
DeGudicibus SJ
P2888
P304
P356
10.1038/320540A0
P407
P577
1986-04-01T00:00:00Z
P5875
P6179
1040637908