SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling. - Wikidata - wikimedia - TriplyDB

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling.

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling.

http://www.wikidata.org/entity/Q42816235

about

Identification of a novel domain in two mammalian inositol-polyphosphate 5-phosphatases that mediates membrane ruffle localization. The inositol 5-phosphatase skip localizes to the endoplasmic reticulum and translocates to membrane ruffles ...P-Rex2, a new guanine-nucleotide exchange factor for Rac NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis Adaptor protein SLAT modulates Fcgamma receptor-mediated phagocytosis in murine macrophages Granulocyte CEACAM3 is a phagocytic receptor of the innate immune system that mediates recognition and elimination of human-specific pathogens PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.Functions and regulation of circular dorsal ruffles Regulation and function of P-Rex family Rac-GEFs Membrane ruffling requires coordination between type Ialpha phosphatidylinositol phosphate kinase and Rac signaling WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase The C-terminal basic tail of RhoG assists the guanine nucleotide exchange factor trio in binding to phospholipids A mutant of SWAP-70, a phosphatidylinositoltrisphosphate binding protein, transforms mouse embryo fibroblasts, which is inhibited by sanguinarine Alsin is a Rab5 and Rac1 guanine nucleotide exchange factor SWAP-70 regulates c-kit-induced mast cell activation, cell-cell adhesion, and migration Def-6, a guanine nucleotide exchange factor for Rac1, interacts with the skeletal muscle integrin chain alpha7A and influences myoblast differentiation The switch-associated protein 70 (SWAP-70) bundles actin filaments and contributes to the regulation of F-actin dynamics swap70 promotes neural precursor cell cycle exit and oligodendrocyte formation.ERK and phosphoinositide 3-kinase temporally coordinate different modes of actin-based motility during embryonic wound healing.RalA activation at nascent lamellipodia of epidermal growth factor-stimulated Cos7 cells and migrating Madin-Darby canine kidney cells.Diagnostic surface expression of SWAP-70 on HIV-1 infected T cells.SWAP-70-like adapter of T cells: a novel Lck-regulated guanine nucleotide exchange factor coordinating actin cytoskeleton reorganization and Ca2+ signaling in T cells SLAT/Def6 plays a critical role in the development of Th17 cell-mediated experimental autoimmune encephalomyelitis.Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.IRF4 and its regulators: evolving insights into the pathogenesis of inflammatory arthritis?Identification of 4 novel HLA-B*40:01 restricted minor histocompatibility antigens and their potential as targets for graft-versus-leukemia reactivity T cell receptor engagement leads to the recruitment of IBP, a novel guanine nucleotide exchange factor, to the immunological synapse.Loss of IRF-4-binding protein leads to the spontaneous development of systemic autoimmunity Regulation of P-Rex1 by phosphatidylinositol (3,4,5)-trisphosphate and Gbetagamma subunits.Signaling protein SWAP-70 is required for efficient B cell homing to lymphoid organs.Alloantigen-presenting plasmacytoid dendritic cells mediate tolerance to vascularized grafts.Cooperation of DEF6 with activated Rac in regulating cell morphology.Expression and localization of SWAP-70 in human fetomaternal interface and placenta during tubal pregnancy and normal placentation.SWAP-70: a new type of oncogene A screen for novel phosphoinositide 3-kinase effector proteins.Regulatory T cells sequentially migrate from inflamed tissues to draining lymph nodes to suppress the alloimmune response.The mechanism of cell membrane ruffling relies on a phospholipase D2 (PLD2), Grb2 and Rac2 association The guanine exchange factor SWAP70 mediates vGPCR-induced endothelial plasticity.Regulation of eosinophil trafficking by SWAP-70 and its role in allergic airway inflammation Impairment of organ-specific T cell negative selection by diabetes susceptibility genes: genomic analysis by mRNA profiling

P2860

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P2860

SWAP-70 is a guanine-nucleotide-exchange factor that mediates signalling of membrane ruffling.

http://www.wikidata.org/entity/Q42816235

description

2002 nî lūn-bûn

@nan

2002年の論文

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2002年論文

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2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

2002年论文

@zh

2002年论文

@zh-cn

name

SWAP-70 is a guanine-nucleotid ...... gnalling of membrane ruffling.

@en

SWAP-70 is a guanine-nucleotid ...... gnalling of membrane ruffling.

@nl

type

label

SWAP-70 is a guanine-nucleotid ...... gnalling of membrane ruffling.

@en

SWAP-70 is a guanine-nucleotid ...... gnalling of membrane ruffling.

@nl

prefLabel

SWAP-70 is a guanine-nucleotid ...... gnalling of membrane ruffling.

@en

SWAP-70 is a guanine-nucleotid ...... gnalling of membrane ruffling.

@nl

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SWAP-70 is a guanine-nucleotid ...... gnalling of membrane ruffling.

@en

P2093

Akihiro Iwamatsu

http://www.w3.org/2001/XMLSchema#string

Azusa Shinohara

http://www.w3.org/2001/XMLSchema#string

Hiroshi Itoh

http://www.w3.org/2001/XMLSchema#string

Maiko Higuchi

http://www.w3.org/2001/XMLSchema#string

Masahiro Shinohara

http://www.w3.org/2001/XMLSchema#string

Naoki Mochizuki

http://www.w3.org/2001/XMLSchema#string

Rolf Jessberger

http://www.w3.org/2001/XMLSchema#string

Satoshi Nagata

http://www.w3.org/2001/XMLSchema#string

Sayoko Ihara

http://www.w3.org/2001/XMLSchema#string

Yasuhisa Fukui

http://www.w3.org/2001/XMLSchema#string

P2860

Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma

Association of SWAP-70 with the B cell antigen receptor complex

EPS8 and E3B1 transduce signals from Ras to Rac

Synthesis and function of 3-phosphorylated inositol lipids

Signalling through the lipid products of phosphoinositide-3-OH kinase

A B-cell-specific DNA recombination complex

A novel mammalian Ras GTPase-activating protein which has phospholipid-binding and Btk homology regions

Role of substrates and products of PI 3-kinase in regulating activation of Rac-related guanosine triphosphatases by Vav

Phosphoinositide kinases

The role of phosphoinositide 3-kinase lipid products in cell function.

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759-763

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scholarly article

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10.1038/416759A

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P433

6882

http://www.w3.org/2001/XMLSchema#string

P478

416

http://www.w3.org/2001/XMLSchema#string

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2002-04-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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1000612576

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11961559

http://www.w3.org/2001/XMLSchema#string