Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins.
about
Catalytic competence of the Ras-GEF domain of hSos1 requires intra-REM domain interactions mediated by phenylalanine 577Sites of phosphorylation by protein kinase A in CDC25Mm/GRF1, a guanine nucleotide exchange factor for Ras.The isolated catalytic hairpin of the Ras-specific guanine nucleotide exchange factor Cdc25Mm retains nucleotide dissociation activity but has impaired nucleotide exchange activity.Characterization and properties of dominant-negative mutants of the ras-specific guanine nucleotide exchange factor CDC25(Mm).
P2860
Mutations at position 1122 in the catalytic domain of the mouse ras-specific guanine nucleotide exchange factor CDC25Mm originate both loss-of-function and gain-of-function proteins.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Mutations at position 1122 in ...... and gain-of-function proteins.
@en
Mutations at position 1122 in ...... and gain-of-function proteins.
@nl
type
label
Mutations at position 1122 in ...... and gain-of-function proteins.
@en
Mutations at position 1122 in ...... and gain-of-function proteins.
@nl
prefLabel
Mutations at position 1122 in ...... and gain-of-function proteins.
@en
Mutations at position 1122 in ...... and gain-of-function proteins.
@nl
P2093
P2860
P50
P1433
P1476
Mutations at position 1122 in ...... and gain-of-function proteins
@en
P2093
P2860
P304
P356
10.1016/S0014-5793(98)01481-1
P407
P577
1998-12-01T00:00:00Z