Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
about
The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phaseS phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain proteinHomeoproteins CDP and SATB1 interact: potential for tissue-specific regulationPU.1 as an essential activator for the expression of gp91(phox) gene in human peripheral neutrophils, monocytes, and B lymphocytesTyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon gamma -induced differentiation of myeloid leukemia cell linesSATB1 makes a complex with p300 and represses gp91(phox) promoter activityPhosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2)PU.1 is essential for p47(phox) promoter activity in myeloid cellsA nuclear matrix attachment region upstream of the T cell receptor beta gene enhancer binds Cux/CDP and SATB1 and modulates enhancer-dependent reporter gene expression but not endogenous gene expressionIdentification and characterization of TF1(phox), a DNA-binding protein that increases expression of gp91(phox) in PLB985 myeloid leukemia cellsThe transcriptional repressor CDP (Cutl1) is essential for epithelial cell differentiation of the lung and the hair follicleA cascade of Ca(2+)/calmodulin-dependent protein kinases regulates the differentiation and functional activation of murine neutrophilsGenetic ablation of the CDP/Cux protein C terminus results in hair cycle defects and reduced male fertilityCut mutant Drosophila auditory organs differentiate abnormally and degenerate.Cux/CDP homeoprotein is a component of NF-muNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activatorMechanisms of expression of NADPH oxidase components in human cultured monocytes: role of cytokines and transcriptional regulators involved.Anaplasma phagocytophilum modulates gp91phox gene expression through altered interferon regulatory factor 1 and PU.1 levels and binding of CCAAT displacement protein.CDP is a repressor of mouse mammary tumor virus expression in the mammary gland.Hoxa9 immortalizes a granulocyte-macrophage colony-stimulating factor-dependent promyelocyte capable of biphenotypic differentiation to neutrophils or macrophages, independent of enforced meis expression.The homeodomain protein CDP regulates mammary-specific gene transcription and tumorigenesis.CDP binding to multiple sites in the mouse mammary tumor virus long terminal repeat suppresses basal and glucocorticoid-induced transcriptionCUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers.The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase.Identification of genetic loci that interact with cut during Drosophila wing-margin development.The homeobox gene cut interacts genetically with the homeotic genes proboscipedia and AntennapediaRAS transformation requires CUX1-dependent repair of oxidative DNA damage.Differentiation-induced cleavage of Cutl1/CDP generates a novel dominant-negative isoform that regulates mammary gene expression.CCAAT displacement protein, a regulator of differentiation-specific gene expression, binds a negative regulatory element within the 5' end of the human papillomavirus type 6 long control region.C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut).The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy.p110 CUX1 cooperates with E2F transcription factors in the transcriptional activation of cell cycle-regulated genes.Lessons from Anaplasma phagocytophilum: chromatin remodeling by bacterial effectors.CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2FThe homeodomain protein Cux1 interacts with Grg4 to repress p27 kip1 expression during kidney development.Regulation of cell proliferation and differentiation in the kidney.Antisense oligonucleotides to Cux-1, a Cut-related homeobox gene, cause increased apoptosis in mouse embryonic kidney culturesThe matrix attachment region-binding protein SATB1 interacts with multiple elements within the gp91phox promoter and is down-regulated during myeloid differentiation.CCAAT displacement activity involves CUT repeats 1 and 2, not the CUT homeodomain.Eosinophil-specific regulation of gp91(phox) gene expression by transcription factors GATA-1 and GATA-2.YY1 binds five cis-elements and trans-activates the myeloid cell-restricted gp91(phox) promoter.
P2860
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P2860
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
@en
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
@nl
type
label
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
@en
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
@nl
prefLabel
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
@en
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells.
@nl
P2860
P356
P1476
Repressor activity of CCAAT displacement protein in HL-60 myeloid leukemia cells
@en
P2093
J J Donady
P M Lievens
P2860
P304
12745-12750
P356
10.1074/JBC.270.21.12745
P407
P577
1995-05-01T00:00:00Z