Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein.
about
The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phaseS phase-specific proteolytic cleavage is required to activate stable DNA binding by the CDP/Cut homeodomain proteinHomeoproteins CDP and SATB1 interact: potential for tissue-specific regulationCCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcriptionThe role of CDP in the negative regulation of CXCL1 gene expressionRegulation of the homeodomain CCAAT displacement/cut protein function by histone acetyltransferases p300/CREB-binding protein (CBP)-associated factor and CBPPhosphorylation of the CCAAT displacement protein (CDP)/Cux transcription factor by cyclin A-Cdk1 modulates its DNA binding activity in G(2)A nuclear matrix attachment region upstream of the T cell receptor beta gene enhancer binds Cux/CDP and SATB1 and modulates enhancer-dependent reporter gene expression but not endogenous gene expressionInactivating CUX1 mutations promote tumorigenesisIdentification and characterization of TF1(phox), a DNA-binding protein that increases expression of gp91(phox) in PLB985 myeloid leukemia cellsIsoforms of hepatocyte nuclear factor-6 differ in DNA-binding properties, contain a bifunctional homeodomain, and define the new ONECUT class of homeodomain proteinsNegative transcriptional modulation and silencing of the bi-exonic Rnf35 gene in the preimplantation embryo. Binding of the CCAAT-displacement protein/Cux to the untranslated exon 1 sequenceCux/CDP homeoprotein is a component of NF-muNR and represses the immunoglobulin heavy chain intronic enhancer by antagonizing the bright transcription activatorRegulation of Fto/Ftm gene expression in mice and humans.Nuclear matrix attachment regions of human papillomavirus type 16 repress or activate the E6 promoter, depending on the physical state of the viral DNA.CDP is a repressor of mouse mammary tumor virus expression in the mammary gland.Repression of human cytomegalovirus major immediate early gene expression by the cellular transcription factor CCAAT displacement protein.The homeodomain protein CDP regulates mammary-specific gene transcription and tumorigenesis.CDP binding to multiple sites in the mouse mammary tumor virus long terminal repeat suppresses basal and glucocorticoid-induced transcriptionA survey of 178 NF-Y binding CCAAT boxes.Cut-like homeobox 1 (CUX1) regulates expression of the fat mass and obesity-associated and retinitis pigmentosa GTPase regulator-interacting protein-1-like (RPGRIP1L) genes and coordinates leptin receptor signaling.The p110 isoform of the CDP/Cux transcription factor accelerates entry into S phase.The homeobox gene cut interacts genetically with the homeotic genes proboscipedia and AntennapediaRAS transformation requires CUX1-dependent repair of oxidative DNA damage.Differentiation-induced cleavage of Cutl1/CDP generates a novel dominant-negative isoform that regulates mammary gene expression.CCAAT displacement protein, a regulator of differentiation-specific gene expression, binds a negative regulatory element within the 5' end of the human papillomavirus type 6 long control region.Special AT-rich Sequence-binding Protein 1 (SATB1) Functions as an Accessory Factor in Base Excision Repair.C/EBP epsilon mediates myeloid differentiation and is regulated by the CCAAT displacement protein (CDP/cut).Interaction of the CCAAT displacement protein with shared regulatory elements required for transcription of paired histone genes.The human cut homeodomain protein can repress gene expression by two distinct mechanisms: active repression and competition for binding site occupancy.DNA-binding specificity of the cut repeats from the human cut-like proteinPDZ domain-mediated dimerization and homeodomain-directed specificity are required for high-affinity DNA binding by SATB1Hypomorphism of Fto and Rpgrip1l causes obesity in mice.CDP/cut is the DNA-binding subunit of histone gene transcription factor HiNF-D: a mechanism for gene regulation at the G1/S phase cell cycle transition point independent of transcription factor E2FRegulation of cell proliferation and differentiation in the kidney.CCAAT displacement activity involves CUT repeats 1 and 2, not the CUT homeodomain.NF-Y and CCAAT/enhancer-binding protein alpha synergistically activate the mouse amelogenin gene.Differential regulation of CDP/Cux p110 by cyclin A/Cdk2 and cyclin A/Cdk1.CCAAT displacement protein (CDP/cut) binds a negative regulatory element in the human tryptophan hydroxylase gene.Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut.
P2860
Q24533294-6CDFE976-85D1-45A2-AA4D-07C78259C8EDQ24550847-FCE18C6C-C059-4497-8787-75B9FB741ECBQ24554476-2E378E05-5EC3-4AA3-B522-556D7DE28268Q24564281-FB383C9A-F23B-4B82-9A07-FE7AFC1C85ECQ24647127-83F6ADBC-354A-4B2F-A8AD-084DABE6E329Q24682599-595656B2-0CBA-441E-8719-8A029AA2B8C8Q28189989-19A4AC64-CF8F-4FB3-8D56-EEDA24C02A4FQ28287052-47641C0D-D0D4-487A-AD00-8C17AAFCAF3CQ28303563-F755EEEF-8BF7-4150-B014-79112EBD3F12Q28306729-DE6F7F36-0EED-4C89-B838-025E9E5EA785Q28577680-D8E7F90A-EB39-477D-8654-D47E0CAB1C99Q28585985-F389371B-39C1-4232-97FA-63924E46979FQ31951342-019C8597-C3F6-4C35-B2ED-04776A6F3D4BQ33599999-7B1D275C-66E9-4F9E-A836-ACB08DEFF28FQ33799469-FE910958-1D16-4440-973B-B25BC34C39C4Q33807563-57C712FE-3642-44E7-97C1-3BF5759C7396Q33835064-87126154-E7D9-450E-9F25-237EDEB2CFF9Q34180702-89239021-94A6-4045-9705-D2D7A23D584FQ34331744-7C9CBF1A-9A60-4F11-8BBB-1C28360D5645Q34456946-49AEDDBE-BE83-426A-832A-4FA3435E4393Q34503227-2E234463-F8D5-40D0-9CDF-C51FEF3F4AF6Q34519903-ECD6BE2E-0461-4B15-8515-D4F27A0399A8Q34604374-27BB6436-31DA-410B-8AD1-5878340E0717Q35117739-CB849ECB-EA47-4914-A730-A364B4C7D4D1Q35131745-CE2CD4CC-1F7A-4FD3-AAEE-87607A832619Q35878106-F3D48A95-E39F-4AD6-A840-EF7F87A71C62Q36122095-50DEA509-C361-4DBD-88F5-35E0037110E2Q36534938-2330102B-6AB3-4647-970A-572A2652C78CQ36552416-CA757F33-205E-4B7E-91E1-DB0782277D47Q36562577-B9265BC6-2DF8-4691-AAB0-7DCB38915ACCQ36566411-3D76914B-BE8E-494A-92F6-75C2E4FCD52EQ36633163-F2837C66-E800-4793-91CC-9797A66B6B5BQ36867329-C19108FD-466F-47C2-AA6B-6581A10153F0Q37256817-61045C0B-FF55-456B-9013-662BE80D9355Q37359013-E1E90DE4-BAFB-42F8-B9ED-753EBC90E766Q38311176-E8F49B53-9A8A-4B91-989E-8ADF876D41C8Q38314496-84F2091F-BA1F-4EB8-A2CA-09B70CA3F8CBQ38322559-B4475D02-B70B-4385-8719-964DDA354ADFQ38329545-24AF2B6F-CAE8-46C2-88DC-21D059BE4E3BQ38353128-363373DF-023F-4170-BCF2-7B76CC3B9DB8
P2860
Sequence-specific DNA binding of individual cut repeats of the human CCAAT displacement/cut homeodomain protein.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Sequence-specific DNA binding ...... ement/cut homeodomain protein.
@ast
Sequence-specific DNA binding ...... ement/cut homeodomain protein.
@en
type
label
Sequence-specific DNA binding ...... ement/cut homeodomain protein.
@ast
Sequence-specific DNA binding ...... ement/cut homeodomain protein.
@en
prefLabel
Sequence-specific DNA binding ...... ement/cut homeodomain protein.
@ast
Sequence-specific DNA binding ...... ement/cut homeodomain protein.
@en
P2093
P2860
P356
P1476
Sequence-specific DNA binding ...... ement/cut homeodomain protein.
@en
P2093
P2860
P304
P356
10.1073/PNAS.91.16.7757
P407
P577
1994-08-01T00:00:00Z