Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2. - Wikidata - wikimedia - TriplyDB

Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2.

Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2.

http://www.wikidata.org/entity/Q42828385

about

Biology of Beige Adipocyte and Possible Therapy for Type 2 Diabetes and Obesity Adipose tissue plasticity: how fat depots respond differently to pathophysiological cues Intracellular Theileria annulata promote invasive cell motility through kinase regulation of the host actin cytoskeleton MAP4K4: an emerging therapeutic target in cancer Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion Adipose Tissue-Specialized Immunologic Features Might Be the Potential Therapeutic Target of Prospective Medicines for Obesity.Map4k4 negatively regulates peroxisome proliferator-activated receptor (PPAR) gamma protein translation by suppressing the mammalian target of rapamycin (mTOR) signaling pathway in cultured adipocytes.MAP4K4 is a novel MAPK/ERK pathway regulator required for lung adenocarcinoma maintenance.Gene expression pathways of high grade localized prostate cancer.RNAi screens reveal novel metabolic regulators: RIP140, MAP4k4 and the lipid droplet associated fat specific protein (FSP) 27.Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes.beta3-adrenergic receptor induction of adipocyte inflammation requires lipolytic activation of stress kinases p38 and JNK TNF-α involvement in insulin resistance induced by experimental scorpion envenomation Fractalkine (CX3CL1), a new factor protecting β-cells against TNFα Association of common genetic variants in the MAP4K4 locus with prediabetic traits in humans.Bimodal effect on pancreatic β-cells of secretory products from normal or insulin-resistant human skeletal muscle A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer.TNF-alpha and adipocyte biology.MiR-194, commonly repressed in colorectal cancer, suppresses tumor growth by regulating the MAP4K4/c-Jun/MDM2 signaling pathway.MicroRNA-30d induces insulin transcription factor MafA and insulin production by targeting mitogen-activated protein 4 kinase 4 (MAP4K4) in pancreatic β-cells.ICF, an immunodeficiency syndrome: DNA methyltransferase 3B involvement, chromosome anomalies, and gene dysregulation Nuclear factor-kappaB is a critical mediator of Ste20-like proline-/alanine-rich kinase regulation in intestinal inflammation Differential regulation of TNF receptor 1 and receptor 2 in adiponectin expression following myocardial ischemia Map4k4 Signaling Nodes in Metabolic and Cardiovascular Diseases Impaired preadipocyte differentiation in human abdominal obesity: role of Wnt, tumor necrosis factor-alpha, and inflammation.A PP2A regulatory subunit regulates C. elegans insulin/IGF-1 signaling by modulating AKT-1 phosphorylation The inflammatory kinase MAP4K4 promotes reactivation of Kaposi's sarcoma herpesvirus and enhances the invasiveness of infected endothelial cells Ste20-related proline/alanine-rich kinase: a novel regulator of intestinal inflammation.Inflammation and impaired adipogenesis in hypertrophic obesity in man.Germinal center kinases in immune regulation.Functional analysis of a novel, thyroglobulin-embedded microRNA gene deregulated in papillary thyroid carcinoma.Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation.mRNA of the pro-apoptotic gene BBC3 serves as a molecular marker for TNF-α-induced islet damage in humans.GO6976 prevents TNF-alpha-induced suppression of adiponectin expression in 3T3-L1 adipocytes: putative involvement of protein kinase C.Glucan particles for selective delivery of siRNA to phagocytic cells in mice.RBM4a-SRSF3-MAP4K4 Splicing Cascade Constitutes a Molecular Mechanism for Regulating Brown Adipogenesis

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P2860

Tumor necrosis factor alpha (TNFalpha) stimulates Map4k4 expression through TNFalpha receptor 1 signaling to c-Jun and activating transcription factor 2.

http://www.wikidata.org/entity/Q42828385

description

2007 nî lūn-bûn

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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2007年论文

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2007年论文

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name

Tumor necrosis factor alpha (T ...... vating transcription factor 2.

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type

label

Tumor necrosis factor alpha (T ...... vating transcription factor 2.

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prefLabel

Tumor necrosis factor alpha (T ...... vating transcription factor 2.

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P1433

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P1433

Journal of Biological Chemistry

P1476

Tumor necrosis factor alpha (T ...... vating transcription factor 2.

@en

P2093

Adilson Guilherme

http://www.w3.org/2001/XMLSchema#string

Andrea C Hubbard

http://www.w3.org/2001/XMLSchema#string

Anil Chawla

http://www.w3.org/2001/XMLSchema#string

Gregory J Tesz

http://www.w3.org/2001/XMLSchema#string

Kalyani V P Guntur

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Michael P Czech

http://www.w3.org/2001/XMLSchema#string

Xiaoqing Tang

http://www.w3.org/2001/XMLSchema#string

P2860

A novel human STE20-related protein kinase, HGK, that specifically activates the c-Jun N-terminal kinase signaling pathway

The Traf2- and Nck-interacting kinase as a putative effector of Rap2 to regulate actin cytoskeleton

Identification and functional characterization of a novel human misshapen/Nck interacting kinase-related kinase, hMINK beta

p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation

A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase

The STE20 kinase HGK is broadly expressed in human tumor cells and can modulate cellular transformation, invasion, and adhesion

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver

Transcription factor ATF2 regulation by the JNK signal transduction pathway

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19302-19312

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scholarly article

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10.1074/JBC.M700665200

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P433

27

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P478

282

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P577

2007-05-11T00:00:00Z

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P698

17500068

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