Remote homology between Munc13 MUN domain and vesicle tethering complexes.
about
Structural basis for the wobbler mouse neurodegenerative disorder caused by mutation in the Vps54 subunit of the GARP complexThe Crystal Structure of a Munc13 C-terminal Module Exhibits a Remarkable Similarity to Vesicle Tethering FactorsCAPS and Munc13 utilize distinct PIP2-linked mechanisms to promote vesicle exocytosisMunc13 mediates the transition from the closed syntaxin-Munc18 complex to the SNARE complexER Import Sites and Their Relationship to ER Exit Sites: A New Model for Bidirectional ER-Golgi Transport in Higher PlantsMunc13-4 functions as a Ca2+ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles.BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cellsMembrane bridging and hemifusion by denaturated Munc18.At the junction of SNARE and SM protein function.Novel interactions of CAPS (Ca2+-dependent activator protein for secretion) with the three neuronal SNARE proteins required for vesicle fusion.Transport according to GARP: receiving retrograde cargo at the trans-Golgi network.Show me the MUN-y.Munc13-4*rab27 complex tethers secretory lysosomes at the plasma membrane.Enlightening molecular mechanisms through study of protein interactionsSyntaxin opening by the MUN domain underlies the function of Munc13 in synaptic-vesicle primingFunctional synergy between the Munc13 C-terminal C1 and C2 domains.A Munc13-like protein in Arabidopsis mediates H+-ATPase translocation that is essential for stomatal responses.Reconstitution of the vital functions of Munc18 and Munc13 in neurotransmitter release.The Vesicle Priming Factor CAPS Functions as a Homodimer via C2 Domain Interactions to Promote Regulated Vesicle Exocytosis.Sec3 promotes the initial binary t-SNARE complex assembly and membrane fusion.Role of vesicle tethering factors in the ER-Golgi membrane traffic.Mechanistic insights into neurotransmitter release and presynaptic plasticity from the crystal structure of Munc13-1 C1C2BMUN.Familial hemophagocytic lymphohistiocytosis: when rare diseases shed light on immune system functioning.Patterns and processes in the evolution of the eukaryotic endomembrane system.Role of PI(4,5)P(2) in vesicle exocytosis and membrane fusion.The DSL1 complex: the smallest but not the least CATCHR.Late steps in secretory lysosome exocytosis in cytotoxic lymphocytes.CAPS and Munc13: CATCHRs that SNARE VesiclesThe biogenesis of lysosomes and lysosome-related organellesFunctional homologies in vesicle tethering.Autoinhibition of Munc18-1 modulates synaptobrevin binding and helps to enable Munc13-dependent regulation of membrane fusion.Diverse Functions and Signal Transduction of the Exocyst Complex in Tumor Cells.Munc13 homology domain-1 in CAPS/UNC31 mediates SNARE binding required for priming vesicle exocytosis.A cascade of multiple proteins and lipids catalyzes membrane fusion.Hypothesis - buttressed rings assemble, clamp, and release SNAREpins for synaptic transmission.Ride the wave: Retrograde trafficking becomes Ca2+ dependent with BAIAP3.Mechanism of neurotransmitter release coming into focus
P2860
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P2860
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
2009年论文
@zh
2009年论文
@zh-cn
name
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
@en
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
@nl
type
label
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
@en
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
@nl
prefLabel
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
@en
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
@nl
P2860
P1476
Remote homology between Munc13 MUN domain and vesicle tethering complexes.
@en
P2093
P2860
P304
P356
10.1016/J.JMB.2009.06.054
P407
P577
2009-06-27T00:00:00Z