Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
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Crystal Structure of SUMO-Modified Proliferating Cell Nuclear AntigenStructural insights into the assembly of human translesion polymerase complexesRecognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2Peeling away the layers of ubiquitin signaling complexities with synthetic ubiquitin-protein conjugates.A bacterial genetic selection system for ubiquitylation cascade discoverySynthetic Proteins and Peptides for the Direct Interrogation of α-Synuclein Posttranslational Modifications53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark.Chemical and semisynthesis of posttranslationally modified proteins.The challenge of producing ubiquitinated proteins for structural studiesSumoylated human histone H4 prevents chromatin compaction by inhibiting long-range internucleosomal interactions.Structurally distinct ubiquitin- and sumo-modified PCNA: implications for their distinct roles in the DNA damage response.Solution X-ray scattering combined with computational modeling reveals multiple conformations of covalently bound ubiquitin on PCNAUbiquitination of the Dishevelled DIX domain blocks its head-to-tail polymerizationA novel ubiquitin binding mode in the S. cerevisiae translesion synthesis DNA polymerase ηSemisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation.Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin.Chemical Methods for Encoding and Decoding of Posttranslational ModificationsUnraveling the complexity of ubiquitin signalingTransient kinetic analysis of USP2-catalyzed deubiquitination reveals a conformational rearrangement in the K48-linked diubiquitin substrateEnzymatic production of mono-ubiquitinated proteins for structural studies: The example of the Josephin domain of ataxin-3.Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein.Chemical Protein Ubiquitylation with Preservation of the Native Cysteine Residues.Synthesis of proteins with defined posttranslational modifications using the genetic noncanonical amino acid incorporation approach.Nonenzymatic ubiquitylation.Ubiquitination of PCNA and its essential role in eukaryotic translesion synthesis.Chemistry and biology of the ubiquitin signal.Chemical strategies to understand the language of ubiquitin signaling.Using chemistry to investigate the molecular consequences of protein ubiquitylation.Pushing the Boundaries of Chemical Protein Synthesis: The Case of Ubiquitin Chains and Polyubiquitinated Peptides and Proteins.Chemical and semisynthetic approaches to study and target deubiquitinases.Chemical ubiquitination for decrypting a cellular code.Structural insights into the catalysis and regulation of E3 ubiquitin ligases.Monoubiquitination Inhibits the Actin Bundling Activity of Fascin.SUMOylated RanGAP1 prepared by click chemistry.Site-specific monoubiquitination activates Ras by impeding GTPase-activating protein functionExploring chemoselective S-to-N acyl transfer reactions in synthesis and chemical biology.Biological and Physicochemical Functions of Ubiquitylation Revealed by Synthetic Chemistry Approaches.Ubiquitylation Directly Induces Fold Destabilization of ProteinsSynthetic biology approach to reconstituting the ubiquitylation cascade in bacteria.Biological applications of protein splicing.
P2860
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P2860
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh-hant
name
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
@en
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
@nl
type
label
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
@en
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
@nl
prefLabel
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
@en
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis.
@nl
P2093
P356
P1476
Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis
@en
P2093
Jialiang Wang
Junjun Chen
Lajos Haracska
Yongxing Ai
P2888
P304
P356
10.1038/NCHEMBIO.316
P577
2010-03-07T00:00:00Z