Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends.
about
Peptides that bind the HIV-1 integrase and modulate its enzymatic activity--kinetic studies and mode of actionLocalization of ASV integrase-DNA contacts by site-directed crosslinking and their structural analysisDolutegravir interactions with HIV-1 integrase-DNA: structural rationale for drug resistance and dissociation kineticsRevealing domain structure through linker-scanning analysis of the murine leukemia virus (MuLV) RNase H and MuLV and human immunodeficiency virus type 1 integrase proteinsAn unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF.Peptides derived from HIV-1 integrase that bind Rev stimulate viral genome integration.Impact of Y143 HIV-1 integrase mutations on resistance to raltegravir in vitro and in vivo.Subunit-specific protein footprinting reveals significant structural rearrangements and a role for N-terminal Lys-14 of HIV-1 Integrase during viral DNA bindingCryo-EM structures and atomic model of the HIV-1 strand transfer complex intasomeStructural properties of HIV integrase. Lens epithelium-derived growth factor oligomers.Resistance to integrase inhibitors.Structure-based modeling of the functional HIV-1 intasome and its inhibitionPeptides that inhibit HIV-1 integrase by blocking its protein-protein interactions.Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity.Retroviral Integrase Structure and DNA Recombination MechanismRetroviral integrases promote fraying of viral DNA ends.Inhibition of HIV-1 integrase nuclear import and replication by a peptide bearing integrase putative nuclear localization signalInhibiting HIV-1 integrase by shifting its oligomerization equilibriumComputer tools in the discovery of HIV-1 integrase inhibitorsStructural biology of retroviral DNA integration.Catalytically-active complex of HIV-1 integrase with a viral DNA substrate binds anti-integrase drugs.Piecing together the structure of retroviral integrase, an important target in AIDS therapyHIV-1 Integrase-DNA Recognition Mechanisms.Probing of HIV-1 integrase/DNA interactions using novel analogs of viral DNA.Molecular dynamics of HIV1-integrase in complex with 93del - a structural perspective on the mechanism of inhibition.Specificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase {alpha}4 helix.Novel regulation of HIV-1 replication and pathogenicity: Rev inhibition of integration.Current Peptide and Protein Candidates Challenging HIV Therapy beyond the Vaccine Era.Crosslinking and mass spectrometry suggest that the isolated NTD domain dimer of Moloney murine leukemia virus integrase adopts a parallel arrangement in solutionNucleocytoplasmic shuttling of HIV-1 integrase is controlled by the viral Rev protein.Defining the DNA substrate binding sites on HIV-1 integrase.Changes to the HIV long terminal repeat and to HIV integrase differentially impact HIV integrase assembly, activity, and the binding of strand transfer inhibitors.Degradation and remobilization of endogenous retroviruses by recombination during the earliest stages of a germ-line invasion
P2860
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P2860
Identification of amino acids in HIV-1 and avian sarcoma virus integrase subsites required for specific recognition of the long terminal repeat Ends.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
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2005年學術文章
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2005年學術文章
@zh-hant
name
Identification of amino acids ...... the long terminal repeat Ends.
@en
Identification of amino acids ...... the long terminal repeat Ends.
@nl
type
label
Identification of amino acids ...... the long terminal repeat Ends.
@en
Identification of amino acids ...... the long terminal repeat Ends.
@nl
prefLabel
Identification of amino acids ...... the long terminal repeat Ends.
@en
Identification of amino acids ...... the long terminal repeat Ends.
@nl
P2093
P2860
P356
P1476
Identification of amino acids ...... the long terminal repeat Ends.
@en
P2093
Aiping Chen
Irene T Weber
Jonathan Leis
Robert W Harrison
P2860
P304
P356
10.1074/JBC.M510628200
P407
P577
2005-11-18T00:00:00Z