about
The human BTG2/TIS21/PC3 gene: genomic structure, transcriptional regulation and evaluation as a candidate tumor suppressor geneRecommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice.Data mining the p53 pathway in the Fugu genome: evidence for strong conservation of the apoptotic pathway.Reassessment of the TP53 mutation database in human disease by data mining with a library of TP53 missense mutations.A functional analysis of p53 during early development of Xenopus laevis.The p53 tumor suppressor gene: from molecular biology to clinical investigation.Targeted expression of oncogenic K-ras in intestinal epithelium causes spontaneous tumorigenesis in mice.The history of p53. A perfect example of the drawbacks of scientific paradigms.Mutations in TP53 are exclusively associated with del(17p) in multiple myelomaLack of HIN-1 methylation defines specific breast tumor subtypes including medullary carcinoma of the breast and BRCA1-linked tumors.Data-driven unbiased curation of the TP53 tumor suppressor gene mutation database and validation by ultradeep sequencing of human tumors.The TP53 colorectal cancer international collaborative study on the prognostic and predictive significance of p53 mutation: influence of tumor site, type of mutation, and adjuvant treatment.p53 gene mutation: software and database.Splice mutations in the p53 gene: case report and review of the literature.The UMD-p53 database: new mutations and analysis tools.Significance of TP53 mutations in human cancer: a critical analysis of mutations at CpG dinucleotides.p53 mutations and resistance to chemotherapy: A stab in the back for p73.Analysis of TP53 mutation status in human cancer cell lines: a reassessmentDetection of p73 antibodies in patients with various types of cancer: immunological characterization.Stabilization and expression of high levels of p53 during early development in Xenopus laevis.p53 alterations in human cancer: more questions than answers.DNA-binding properties of the major structural protein of simian virus 40Shaping genetic alterations in human cancer: the p53 mutation paradigm.TP53 mutations in human cancer: database reassessment and prospects for the next decade.Advances in carcinogenesis: a historical perspective from observational studies to tumor genome sequencing and TP53 mutation spectrum analysis.Locus-specific databases in cancer: what future in a post-genomic era? The TP53 LSDB paradigm.TP53 mutations in human cancer: database reassessment and prospects for the next decade.Recommendations for analyzing and reporting TP53 gene variants in the high-throughput sequencing era.The TP53 gene network in a postgenomic era.Xenopus laevis p53 protein: sequence-specific DNA binding, transcriptional regulation and oligomerization are evolutionarily conserved.Regulation of mutant p53 temperature-sensitive DNA binding.p53 immunolabeling in archival paraffin-embedded tissues: optimal protocol based on microwave heating for eight antibodies on lung carcinomas.TP53: an oncogene in disguise.TP53 and 53BP1 Reunited.Monitoring of p53 autoantibodies in lung cancer during therapy: relationship to response to treatment.Prognostic significance of serum p53 antibodies in patients with limited-stage small cell lung cancer.Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and the lacZ gene in transgenic rodents.Databases and software for the analysis of mutations in the human p53 gene, the human hprt gene and both the lacI and lacZ gene in transgenic rodents.Genetic profiling of CLL: a 'TP53 addict' perspective.Can we predict solar ultraviolet radiation as the causal event in human tumours by analysing the mutation spectra of the p53 gene?
P50
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P50
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Thierry Soussi
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P1153
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P21
P2456
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P4450
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