Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.
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The S4–S5 Linker Acts as a Signal Integrator for hERG K+ Channel Activation and Deactivation GatingMolecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating.Mutations within the S4-S5 linker alter voltage sensor constraints in hERG K+ channels.Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channelOpposite Effects of the S4-S5 Linker and PIP(2) on Voltage-Gated Channel Function: KCNQ1/KCNE1 and Other Channels.Bimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels.Cytoplasmic domains and voltage-dependent potassium channel gating.Voltage-dependent gating of HERG potassium channels.Getting to the heart of hERG K(+) channel gating.Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains.Tyrosine Residues from the S4-S5 Linker of Kv11.1 Channels Are Critical for Slow DeactivationInteractions between the N-terminal tail and the gating machinery of hERG K⁺ channels both in closed and open/inactive states.Regional flexibility in the S4-S5 linker regulates hERG channel closed-state stabilization.Gating mechanism of Kv11.1 (hERG) K+ channels without covalent connection between voltage sensor and pore domains.Ether-à-go-go K+ channels: effective modulators of neuronal excitability.Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels.Stabilization of the Activated hERG Channel Voltage Sensor by Depolarization Involves the S4-S5 Linker.Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain.Relative positioning of Kv11.1 (hERG) K channel cytoplasmic domain-located fluorescent tags toward the plasma membrane
P2860
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P2860
Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.
description
2008 nî lūn-bûn
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2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Thermodynamic and kinetic prop ...... under steady-state conditions.
@en
Thermodynamic and kinetic prop ...... under steady-state conditions.
@nl
type
label
Thermodynamic and kinetic prop ...... under steady-state conditions.
@en
Thermodynamic and kinetic prop ...... under steady-state conditions.
@nl
prefLabel
Thermodynamic and kinetic prop ...... under steady-state conditions.
@en
Thermodynamic and kinetic prop ...... under steady-state conditions.
@nl
P2860
P50
P1433
P1476
Thermodynamic and kinetic prop ...... under steady-state conditions
@en
P2093
Carlos Alonso-Ron
P2860
P304
P356
10.1529/BIOPHYSJ.107.116731
P407
P577
2008-01-25T00:00:00Z