Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment.
about
Structural properties of PAS domains from the KCNH potassium channelsStructure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanismCalmodulin Regulates Human Ether à Go-Go 1 (hEAG1) Potassium Channels through Interactions of the Eag Domain with the Cyclic Nucleotide Binding Homology DomainCarboxy-terminal domain mediates assembly of the voltage-gated rat ether-à-go-go potassium channelRapid internalization of the oncogenic K+ channel K(V)10.1Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic gangliaCalmodulin interaction with hEAG1 visualized by FRET microscopyConcerted all-or-none subunit interactions mediate slow deactivation of human ether-à-go-go-related gene K+ channelsThe N-terminus of the K channel KAT1 controls its voltage-dependent gating by altering the membrane electric field.Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels.The Eag domain regulates the voltage-dependent inactivation of rat Eag1 K+ channels.Intracellular regions of the Eag potassium channel play a critical role in generation of voltage-dependent currents.Mg2+ mediates interaction between the voltage sensor and cytosolic domain to activate BK channelsBimodal regulation of an Elk subfamily K+ channel by phosphatidylinositol 4,5-bisphosphate.Glutamine substitution at alanine1649 in the S4-S5 cytoplasmic loop of domain 4 removes the voltage sensitivity of fast inactivation in the human heart sodium channelFlavonoid regulation of EAG1 channelsA functional Kv1.2-hERG chimaeric channel expressed in Pichia pastorisBK-type calcium-activated potassium channels: coupling of metal ions and voltage sensing.Cytoplasmic domains and voltage-dependent potassium channel gating.The enigmatic cytoplasmic regions of KCNH channels.A novel mutation (T65P) in the PAS domain of the human potassium channel HERG results in the long QT syndrome by trafficking deficiency.Kv10.1 K(+) channel: from physiology to cancer.Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating.Modulation of HERG gating by a charge cluster in the N-terminal proximal domain.A new mechanism of voltage-dependent gating exposed by KV10.1 channels interrupted between voltage sensor and pore.Cysteines control the N- and C-linker-dependent gating of KCNH1 potassium channels.Role of the S4-S5 linker in CNG channel activation.Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions.Cloning and functional characterization of the smooth muscle ether-a-go-go-related gene K+ channel. Potential role of a conserved amino acid substitution in the S4 region.Ether-à-go-go K+ channels: effective modulators of neuronal excitability.Structural insights into the mechanisms of CNBD channel function.Functional characterization of the C-terminus of the human ether-à-go-go-related gene K(+) channel (HERG).Mutations of the S4-S5 linker alter activation properties of HERG potassium channels expressed in Xenopus oocytes.Inhibition of the K+ conductance and Cole-Moore shift of the oncogenic Kv10.1 channel by amiodarone.The pore of plant K(+) channels is involved in voltage and pH sensing: domain-swapping between different K(+) channel alpha-subunits.
P2860
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P2860
Amino terminal-dependent gating of the potassium channel rat eag is compensated by a mutation in the S4 segment.
description
1997 nî lūn-bûn
@nan
1997 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1997 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
name
Amino terminal-dependent gatin ...... a mutation in the S4 segment.
@ast
Amino terminal-dependent gatin ...... a mutation in the S4 segment.
@en
type
label
Amino terminal-dependent gatin ...... a mutation in the S4 segment.
@ast
Amino terminal-dependent gatin ...... a mutation in the S4 segment.
@en
prefLabel
Amino terminal-dependent gatin ...... a mutation in the S4 segment.
@ast
Amino terminal-dependent gatin ...... a mutation in the S4 segment.
@en
P2093
P2860
P1476
Amino terminal-dependent gatin ...... a mutation in the S4 segment.
@en
P2093
P2860
P304
P356
10.1111/J.1469-7793.1997.537BJ.X
P407
P478
502 ( Pt 3)
P577
1997-08-01T00:00:00Z