Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation.
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ATM-mediated phosphorylation activates the tumor-suppressive function of B56γ-PP2ARole of bile salt in regulating Mcl-1 phosphorylation and chemoresistance in hepatocellular carcinoma cellsThe Axin1 scaffold protein promotes formation of a degradation complex for c-MycInhibition of c-Myc activity by ribosomal protein L11Identification of PP2A complexes and pathways involved in cell transformationNuclear export and centrosome targeting of the protein phosphatase 2A subunit B56alpha: role of B56alpha in nuclear export of the catalytic subunitTargeting protein serine/threonine phosphatases for drug developmentThe broken "Off" switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillanceProtein Phosphatase 2A as a Therapeutic Target in Acute Myeloid LeukemiaCellular prostatic acid phosphatase, a PTEN-functional homologue in prostate epithelia, functions as a prostate-specific tumor suppressorPre-Anchoring of Pin1 to Unphosphorylated c-Myc in a Fuzzy Complex Regulates c-Myc Activity.Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation MotifsMono- or double-site phosphorylation distinctly regulates the proapoptotic function of BaxThe protein phosphatase 2A regulatory subunits B'beta and B'delta mediate sustained TrkA neurotrophin receptor autophosphorylation and neuronal differentiationThe C. elegans RSA complex localizes protein phosphatase 2A to centrosomes and regulates mitotic spindle assemblyProtein kinase A regulates MYC protein through transcriptional and post-translational mechanisms in a catalytic subunit isoform-specific manner.Regulation of c-Myc Protein Abundance by a Protein Phosphatase 2A-Glycogen Synthase Kinase 3β-Negative Feedback Pathway.PP2A-mediated dephosphorylation of p107 plays a critical role in chondrocyte cell cycle arrest by FGFProtein phosphatase 2A-dependent dephosphorylation of replication protein A is required for the repair of DNA breaks induced by replication stressEpigenetic responses to environmental change and their evolutionary implicationsThe tumor suppressor protein HBP1 is a novel c-myc-binding protein that negatively regulates c-myc transcriptional activity.PP2A-B55β antagonizes cyclin E1 proteolysis and promotes its dysregulation in cancer.Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer.A B56gamma mutation in lung cancer disrupts the p53-dependent tumor-suppressor function of protein phosphatase 2ATargeting inhibitors of the tumor suppressor PP2A for the treatment of pancreatic cancerPP2A-mediated regulation of Ras signaling in G2 is essential for stable quiescence and normal G1 length.Myc proteins as therapeutic targets.Protein phosphatase 2A negatively regulates eukaryotic initiation factor 4E phosphorylation and eIF4F assembly through direct dephosphorylation of Mnk and eIF4E.The protein phosphatase 2A regulatory subunit B55α is a modulator of signaling and microRNA expression in acute myeloid leukemia cells.Role of Ku70 in deubiquitination of Mcl-1 and suppression of apoptosis.Decorin antagonizes Met receptor activity and down-regulates {beta}-catenin and Myc levels.A tumor suppressor role for PP2A-B56alpha through negative regulation of c-Myc and other key oncoproteins.Pin1 regulates the dynamics of c-Myc DNA binding to facilitate target gene regulation and oncogenesis.Phosphorylation regulates c-Myc's oncogenic activity in the mammary gland.MYC and Breast Cancer.Frontier of epilepsy research - mTOR signaling pathway.Targeting SET/I(2)PP2A oncoprotein functions as a multi-pathway strategy for cancer therapyDistinct Transcriptomic Features are Associated with Transitional and Mature B-Cell Populations in the Mouse Spleen.Protein phosphatase 2A and neutral sphingomyelinase 2 regulate IRAK-1 protein ubiquitination and degradation in response to interleukin-1betaPhosphatases: the new brakes for cancer development?
P2860
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P2860
Protein phosphatase 2A regulatory subunit B56alpha associates with c-myc and negatively regulates c-myc accumulation.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh-hant
name
Protein phosphatase 2A regulat ...... regulates c-myc accumulation.
@en
Protein phosphatase 2A regulat ...... regulates c-myc accumulation.
@nl
type
label
Protein phosphatase 2A regulat ...... regulates c-myc accumulation.
@en
Protein phosphatase 2A regulat ...... regulates c-myc accumulation.
@nl
prefLabel
Protein phosphatase 2A regulat ...... regulates c-myc accumulation.
@en
Protein phosphatase 2A regulat ...... regulates c-myc accumulation.
@nl
P2860
P1476
Protein phosphatase 2A regulat ...... regulates c-myc accumulation.
@en
P2093
Hugh K Arnold
Rosalie C Sears
P2860
P304
P356
10.1128/MCB.26.7.2832-2844.2006
P407
P577
2006-04-01T00:00:00Z