about
From Gene Targeting to Genome Editing: Transgenic animals applications and beyondRat embryonic stem cells create new era in development of genetically manipulated rat modelsTranscription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines.Generation of Esr1-knockout rats using zinc finger nuclease-mediated genome editing.Dissection of zebrafish shha function using site-specific targeting with a Cre-dependent genetic switchAllele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR-Cas platformEfficient gene targeting by homology-directed repair in rat zygotes using TALE nucleases.Rare inherited kidney diseases: challenges, opportunities, and perspectives.2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research.Convergent functional genomics in addiction research - a translational approach to study candidate genes and gene networksHeritable multiplex genetic engineering in rats using CRISPR/Cas9.Targeted genetic manipulations of neuronal subtypes using promoter-specific combinatorial AAVs in wild-type animalsTissue Specific Expression of Cre in Rat Tyrosine Hydroxylase and Dopamine Active Transporter-Positive Neurons.Homology-directed repair in rodent zygotes using Cas9 and TALEN engineered proteins.Defining functional gene-circuit interfaces in the mouse nervous system.One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering.Model organisms and traditional chinese medicine syndrome models.Nuclease-mediated genome editing: At the front-line of functional genomics technology.The application of somatic CRISPR-Cas9 to conditional genome editing in Caenorhabditis elegans.Genome editing revolutionize the creation of genetically modified pigs for modeling human diseases.Using the CRISPR/Cas9 system to understand neuropeptide biology and regulation.Neurodevelopmental Malformations of the Cerebellar Vermis in Genetically Engineered Rats.From engineering to editing the rat genome.Generating rats with conditional alleles using CRISPR/Cas9.Heritable gene-targeting with gRNA/Cas9 in rats.Genetics-based manipulation of adipose tissue sympathetic innervation.Generating genetically modified mice using CRISPR/Cas-mediated genome engineering.PRONOUNCED HYPERACTIVITY, COGNITIVE DYSFUNCTIONS AND BDNF DYSREGULATION IN DOPAMINE TRANSPORTER KNOCKOUT RATS.DDX4-EGFP transgenic rat model for the study of germline development and spermatogenesis.CRISPR/Cas-mediated genome editing in the rat via direct injection of one-cell embryos.CLICK: one-step generation of conditional knockout mice.
P2860
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P2860
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
@zh-sg
2013年學術文章
@yue
2013年學術文章
@zh-hant
name
Whole-rat conditional gene knockout via genome editing.
@en
Whole-rat conditional gene knockout via genome editing.
@nl
type
label
Whole-rat conditional gene knockout via genome editing.
@en
Whole-rat conditional gene knockout via genome editing.
@nl
prefLabel
Whole-rat conditional gene knockout via genome editing.
@en
Whole-rat conditional gene knockout via genome editing.
@nl
P2093
P2860
P356
P1433
P1476
Whole-rat conditional gene knockout via genome editing.
@en
P2093
Aaron McCoy
Andre Chambers
Andrew J Brown
Daniel A Fisher
Edward J Weinstein
Evguenia Kouranova
Joe Warren
Kevin Forbes
Rachel Henry
P2860
P2888
P304
P356
10.1038/NMETH.2516
P577
2013-06-09T00:00:00Z
P5875
P6179
1036894573