Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
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SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasmPhospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targetingApigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90Threonine 48 in the BIR domain of survivin is critical to its mitotic and anti-apoptotic activities and can be phosphorylated by CK2 in vitroThe pleckstrin homology domain-containing protein CKIP-1 is involved in regulation of cell morphology and the actin cytoskeleton and interaction with actin capping proteinProtein kinase CK2 inhibitor 4,5,6,7-tetrabromobenzotriazole (TBB) induces apoptosis and caspase-dependent degradation of haematopoietic lineage cell-specific protein 1 (HS1) in Jurkat cellsCK2 is responsible for phosphorylation of human La protein serine-366 and can modulate rpL37 5'-terminal oligopyrimidine mRNA metabolismCasein kinase 2 associates with initiation-competent RNA polymerase I and has multiple roles in ribosomal DNA transcriptionStructural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazoleBiochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA)Alternative binding modes of an inhibitor to two different kinasesQuinalizarin as a potent, selective and cell-permeable inhibitor of protein kinase CK2A detailed thermodynamic profile of cyclopentyl and isopropyl derivatives binding to CK2 kinaseCrystal structure of human CK2α at 1.06 Å resolutionCell-permeable dual inhibitors of protein kinases CK2 and PIM-1: structural features and pharmacological potentialDiapause prevention effect of Bombyx mori by dimethyl sulfoxideA phosphatase cascade by which rewarding stimuli control nucleosomal response.DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeepingIdentification of a novel function of CX-4945 as a splicing regulatorRegulation of amyloid precursor protein processing by serotonin signalingRegulation of the proapoptotic functions of prostate apoptosis response-4 (Par-4) by casein kinase 2 in prostate cancer cellsPhosphorylation regulates removal of synaptic N-methyl-D-aspartate receptors after withdrawal from chronic ethanol exposureThe 14-3-3ζ protein binds to the cell adhesion molecule L1, promotes L1 phosphorylation by CKII and influences L1-dependent neurite outgrowthCasein kinase II controls TBK1/IRF3 activation in IFN response against viral infection.Tyrosine phosphorylation of protein kinase CK2 by Src-related tyrosine kinases correlates with increased catalytic activity.A new XRCC1-containing complex and its role in cellular survival of methyl methanesulfonate treatment.Ecto-phosphorylation of CD98 regulates cell-cell interactions.Inhibition of casein kinase 2 blocks G2/M transition in early embryo mitosis but not in oocyte meiosis in mouseWNT signaling and distant metastasis in colon cancer through transcriptional activity of nuclear β-Catenin depend on active PI3K signaling.Casein kinase II regulates N-methyl-D-aspartate receptor activity in spinal cords and pain hypersensitivity induced by nerve injury.Identification of novel CK2 inhibitors with a benzofuran scaffold by novel non-radiometric in vitro assays.Alterations of microRNAs are associated with impaired growth of MCF-7 breast cancer cells induced by inhibition of casein kinase 2.Involvement of protein kinase CK2 in angiogenesis and retinal neovascularizationProtein kinases CK1 and CK2 as new targets for neurodegenerative diseases.Regulation of protein phosphatase 1I by Cdc25C-associated kinase 1 (C-TAK1) and PFTAIRE protein kinase.Casein kinase 2 regulates the NR2 subunit composition of synaptic NMDA receptors.Synergistic interactions of the anti-casein kinase 2 CIGB-300 peptide and chemotherapeutic agents in lung and cervical preclinical cancer models.Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cellsv-Src-dependent down-regulation of the Ste20-like kinase SLK by casein kinase II.Protein kinase CK2 is a central regulator of topoisomerase I hyperphosphorylation and camptothecin sensitivity in cancer cell lines
P2860
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P2860
Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Selectivity of 4,5,6,7-tetrabr ...... inase CK2 ('casein kinase-2').
@en
Selectivity of 4,5,6,7-tetrabr ...... inase CK2 ('casein kinase-2').
@nl
type
label
Selectivity of 4,5,6,7-tetrabr ...... inase CK2 ('casein kinase-2').
@en
Selectivity of 4,5,6,7-tetrabr ...... inase CK2 ('casein kinase-2').
@nl
prefLabel
Selectivity of 4,5,6,7-tetrabr ...... inase CK2 ('casein kinase-2').
@en
Selectivity of 4,5,6,7-tetrabr ...... inase CK2 ('casein kinase-2').
@nl
P2093
P2860
P1433
P1476
Selectivity of 4,5,6,7-tetrabr ...... inase CK2 ('casein kinase-2').
@en
P2093
P2860
P356
10.1016/S0014-5793(01)02404-8
P407
P577
2001-05-01T00:00:00Z