Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance.
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Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosisPTEN blocks tumor necrosis factor-induced NF-kappa B-dependent transcription by inhibiting the transactivation potential of the p65 subunit.Translocation of full-length Bid to mitochondria during anoikis.Transduction of tumor necrosis factor-related apoptosis-inducing ligand into hematopoietic cells leads to inhibition of syngeneic tumor growth in vivo.The TRAIL of oncogenes to apoptosis.Human MUC1 carcinoma-associated protein confers resistance to genotoxic anticancer agents.TRAIL/Apo-2L: mechanisms and clinical applications in cancer.A protein kinase C/protein kinase D pathway protects LNCaP prostate cancer cells from phorbol ester-induced apoptosis by promoting ERK1/2 and NF-{kappa}B activitiesThe RAS signal transduction pathway and its role in radiation sensitivity.TRAIL and apoptosis induction by TNF-family death receptors.Fas-mediated apoptosis in cholangiocarcinoma cells is enhanced by 3,3'-diindolylmethane through inhibition of AKT signaling and FLICE-like inhibitory protein.Heterogeneity in apoptotic responses of microvascular endothelial cells to oxidative stress.Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is required for induction of autophagy during lumen formation in vitroSusceptibility of rheumatoid arthritis synovial fibroblasts to FasL- and TRAIL-induced apoptosis is cell cycle-dependent.Apoptosis induction in renal cell carcinoma by TRAIL and gamma-radiation is impaired by deficient caspase-9 cleavage.Androgens regulate TRAIL-induced cell death in prostate cancer cells via multiple mechanismsThe natural compound Alizarin as an osteotropic drug for the treatment of bone tumors.Roles of the PI3K/Akt pathway and autophagy in TLR3 signaling-induced apoptosis and growth arrest of human prostate cancer cells.Programmed cell death 4 (PDCD4) enhances the sensitivity of gastric cancer cells to TRAIL-induced apoptosis by inhibiting the PI3K/Akt signaling pathway.Inhibition of Akt signaling by the lignan matairesinol sensitizes prostate cancer cells to TRAIL-induced apoptosis.Regulation of Apoptosis by HER2 in Breast Cancer.Gene transfer of CD40-ligand to dendritic cells stimulates interferon-gamma production to induce growth arrest and apoptosis of tumor cells.Mcl-1 as a buffer for proapoptotic Bcl-2 family members during TRAIL-induced apoptosis: a mechanistic basis for sorafenib (Bay 43-9006)-induced TRAIL sensitization.Potential mechanism of resistance to TRAIL-induced apoptosis in Burkitt's lymphoma.HER2 signaling downregulation by trastuzumab and suppression of the PI3K/Akt pathway: an unexpected effect on TRAIL-induced apoptosis.ZD1839 (Gefitinib, 'Iressa'), an epidermal growth factor receptor-tyrosine kinase inhibitor, enhances the anti-cancer effects of TRAIL in human esophageal squamous cell carcinoma.Methylseleninic acid sensitizes prostate cancer cells to TRAIL-mediated apoptosis.Resistance to Apo2 ligand (Apo2L)/tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis and constitutive expression of Apo2L/TRAIL in human T-cell leukemia virus type 1-infected T-cell lines.Amiloride augments TRAIL-induced apoptotic death by inhibiting phosphorylation of kinases and phosphatases associated with the P13K-Akt pathway.Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis by inhibition of Cdc2 and the subsequent downregulation of survivin and XIAP.Roscovitine sensitizes glioma cells to TRAIL-mediated apoptosis by downregulation of survivin and XIAP.Upregulation of FLIP(S) by Akt, a possible inhibition mechanism of TRAIL-induced apoptosis in human gastric cancers.Pretreatment of indole-3-carbinol augments TRAIL-induced apoptosis in a prostate cancer cell line, LNCaP.Elevated Akt phosphorylation as an indicator of renal tubular epithelial cell stress.PTEN sensitizes prostate cancer cells to death receptor-mediated and drug-induced apoptosis through a FADD-dependent pathway.Low glucose-enhanced TRAIL cytotoxicity is mediated through the ceramide-Akt-FLIP pathway.Constitutively active Akt1 protects HL60 leukemia cells from TRAIL-induced apoptosis through a mechanism involving NF-kappaB activation and cFLIP(L) up-regulation.Translation inhibitors sensitize prostate cancer cells to apoptosis induced by tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) by activating c-Jun N-terminal kinase.In vivo gene therapy of human bladder cancer with PTEN suppresses tumor growth, downregulates phosphorylated Akt, and increases sensitivity to doxorubicin.hPEBP4 resists TRAIL-induced apoptosis of human prostate cancer cells by activating Akt and deactivating ERK1/2 pathways.
P2860
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P2860
Pro-survival function of Akt/protein kinase B in prostate cancer cells. Relationship with TRAIL resistance.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Pro-survival function of Akt/p ...... ionship with TRAIL resistance.
@en
Pro-survival function of Akt/p ...... ionship with TRAIL resistance.
@nl
type
label
Pro-survival function of Akt/p ...... ionship with TRAIL resistance.
@en
Pro-survival function of Akt/p ...... ionship with TRAIL resistance.
@nl
prefLabel
Pro-survival function of Akt/p ...... ionship with TRAIL resistance.
@en
Pro-survival function of Akt/p ...... ionship with TRAIL resistance.
@nl
P2093
P2860
P356
P1476
Pro-survival function of Akt/p ...... ionship with TRAIL resistance.
@en
P2093
C Nwokorie
H Robinson
N Onwudiwe
R K Srivastava
S K Pandey
P2860
P304
38361-38369
P356
10.1074/JBC.M103321200
P407
P577
2001-07-18T00:00:00Z