Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.
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Mechanisms of Siglec-F-induced eosinophil apoptosis: a role for caspases but not for SHP-1, Src kinases, NADPH oxidase or reactive oxygenChronic OVA allergen challenged Siglec-F deficient mice have increased mucus, remodeling, and epithelial Siglec-F ligands which are up-regulated by IL-4 and IL-13Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanismsCharacterization of expression of glycan ligands for Siglec-F in normal mouse lungsSialyltransferase ST3Gal-III regulates Siglec-F ligand formation and eosinophilic lung inflammation in miceGalactose 6-O-sulfotransferases are not required for the generation of Siglec-F ligands in leukocytes or lung tissueDevelopmental, malignancy-related, and cross-species analysis of eosinophil, mast cell, and basophil siglec-8 expressionAnti-Siglec-F antibody reduces allergen-induced eosinophilic inflammation and airway remodelingDefining the in vivo function of Siglec-F, a CD33-related Siglec expressed on mouse eosinophilsGenetic mapping of putative Chrna7 and Luzp2 neuronal transcriptional enhancers due to impact of a transgene-insertion and 6.8 Mb deletion in a mouse model of Prader-Willi and Angelman syndromes.Siglecs as sensors of self in innate and adaptive immune responsesSiglecs and immune regulationHigh resolution crystal structures of Siglec-7. Insights into ligand specificity in the Siglec familyMouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6'-sulfo-sialyl Lewis X as a preferred glycan ligandHuman Siglec-10 can bind to vascular adhesion protein-1 and serves as its substrateAltered eosinophil profile in mice with ST6Gal-1 deficiency: an additional role for ST6Gal-1 generated by the P1 promoter in regulating allergic inflammation.Siglec-G/10 in self-nonself discrimination of innate and adaptive immunity.CD33/Siglec-3 binding specificity, expression pattern, and consequences of gene deletion in miceThe role of lung epithelial ligands for Siglec-8 and Siglec-F in eosinophilic inflammation.Osteoclast progenitors reside in the peroxisome proliferator-activated receptor γ-expressing bone marrow cell population.PTP1B deficiency exacerbates inflammation and accelerates leukocyte trafficking in vivo.The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.Distinct endocytic mechanisms of CD22 (Siglec-2) and Siglec-F reflect roles in cell signaling and innate immunity.Host and pathogen hyaluronan signal through human siglec-9 to suppress neutrophil activation.Siglec-8 as a drugable target to treat eosinophil and mast cell-associated conditions.Siglec-8 on human eosinophils and mast cells, and Siglec-F on murine eosinophils, are functionally related inhibitory receptors.IL-3 induces basophil expansion in vivo by directing granulocyte-monocyte progenitors to differentiate into basophil lineage-restricted progenitors in the bone marrow and by increasing the number of basophil/mast cell progenitors in the spleenSiglec-F inhibition reduces esophageal eosinophilia and angiogenesis in a mouse model of eosinophilic esophagitis.Siglec-7 restores β-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes.Siglec-8 and Siglec-F, the new therapeutic targets in asthma.Associations of genetic polymorphisms of Siglecs with human diseases.Glycobiology of Eosinophilic Inflammation: Contributions of Siglecs, Glycans, and Other Glycan-Binding Proteins.Focused microarray analysis of peripheral mononuclear blood cells from Churg-Strauss syndrome patients.Functional evaluation of activation-dependent alterations in the sialoglycan composition of T cellsFrontal affinity chromatography analysis of constructs of DC-SIGN, DC-SIGNR and LSECtin extend evidence for affinity to agalactosylated N-glycans.Human Siglec-5: tissue distribution, novel isoforms and domain specificities for sialic acid-dependent ligand interactions.Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin-dependent function in human eosinophils.
P2860
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P2860
Cloning and characterization of a novel mouse Siglec, mSiglec-F: differential evolution of the mouse and human (CD33) Siglec-3-related gene clusters.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
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2001年學術文章
@zh-hant
name
Cloning and characterization o ...... iglec-3-related gene clusters.
@en
Cloning and characterization o ...... iglec-3-related gene clusters.
@nl
type
label
Cloning and characterization o ...... iglec-3-related gene clusters.
@en
Cloning and characterization o ...... iglec-3-related gene clusters.
@nl
prefLabel
Cloning and characterization o ...... iglec-3-related gene clusters.
@en
Cloning and characterization o ...... iglec-3-related gene clusters.
@nl
P2093
P2860
P356
P1476
Cloning and characterization o ...... Siglec-3-related gene clusters
@en
P2093
P2860
P304
45128-45136
P356
10.1074/JBC.M108573200
P407
P50
P577
2001-09-28T00:00:00Z