Rapamycin's resurrection: a new way to target the cancer cell cycle.
about
Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chipsRapamycin fed late in life extends lifespan in genetically heterogeneous miceOvercoming cisplatin resistance by mTOR inhibitor in lung cancer.Finding Ponce de Leon's Pill: Challenges in Screening for Anti-Aging MoleculesRapalogs in cancer prevention: anti-aging or anticancer?TOR controls transcriptional and translational programs via Sap-Sit4 protein phosphatase signaling effectorsCross talk between estradiol and mTOR kinase in the regulation of ovarian granulosa proliferationProtein kinases--the major drug targets of the twenty-first century?Rapamycin extends murine lifespan but has limited effects on aging.Phase I dose-escalation study of the mTOR inhibitor sirolimus and the HDAC inhibitor vorinostat in patients with advanced malignancy.Rapamycin and mTOR: a serendipitous discovery and implications for breast cancerRapamycin is active against B-precursor leukemia in vitro and in vivo, an effect that is modulated by IL-7-mediated signaling.Selective anti-cancer agents as anti-aging drugsLongevity, aging and rapamycin.Energy restriction and potential energy restriction mimetics.Rapamycin inhibits GM-CSF-induced neutrophil migration.Advances in molecular therapies in patients with brain tumors.Multi-algorithm and multi-model based drug target prediction and web server.The new era in the treatment of advanced colorectal cancer patients: the role of monoclonal antibodies.Design of aging intervention studies: the NIA interventions testing program.Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors.mTOR function in skeletal muscle: a focal point for overnutrition and exercise.A novel rapamycin-polymer conjugate based on a new poly(ethylene glycol) multiblock copolymer.Parameterization of DFTB3/3OB for Sulfur and Phosphorus for Chemical and Biological Applications.Activation of the p70 S6 kinase and phosphorylation of the 4E-BP1 repressor of mRNA translation by type I interferons.Immunosuppressants in cancer prevention and therapyPhosphoinositide 3-Kinase Signaling Pathway in Pancreatic Ductal Adenocarcinoma Progression, Pathogenesis, and Therapeutics.
P2860
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P2860
Rapamycin's resurrection: a new way to target the cancer cell cycle.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh
2001年學術文章
@zh-hant
name
Rapamycin's resurrection: a new way to target the cancer cell cycle.
@en
Rapamycin's resurrection: a new way to target the cancer cell cycle.
@nl
type
label
Rapamycin's resurrection: a new way to target the cancer cell cycle.
@en
Rapamycin's resurrection: a new way to target the cancer cell cycle.
@nl
prefLabel
Rapamycin's resurrection: a new way to target the cancer cell cycle.
@en
Rapamycin's resurrection: a new way to target the cancer cell cycle.
@nl
P356
P1476
Rapamycin's resurrection: a new way to target the cancer cell cycle.
@en
P2093
P304
P356
10.1093/JNCI/93.20.1517
P407
P577
2001-10-01T00:00:00Z