Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17).
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Homeodomain-interacting protein kinase 1 modulates Daxx localization, phosphorylation, and transcriptional activity.Daxx silencing sensitizes cells to multiple apoptotic pathwaysA phase 2 study of vorinostat in acute myeloid leukemiaThe histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responsesVorinostat induces reactive oxygen species and DNA damage in acute myeloid leukemia cellsHistone Deacetylase Inhibitor Romidepsin Has Differential Activity in Core Binding Factor Acute Myeloid LeukemiaA Phase I study of intermittently dosed vorinostat in combination with bortezomib in patients with advanced solid tumorsLeukaemogenesis: more than mutant genesInhibition of the NAD-dependent protein deacetylase SIRT2 induces granulocytic differentiation in human leukemia cells.The promyelocytic leukemia nuclear body: sites of activity?Epigenetic Regulation of Glutamic Acid Decarboxylase 67 in a Hippocampal Circuit.A phase I study of vorinostat in combination with bortezomib in patients with advanced malignancies.Hydroxamic acids (therapeutics and mechanism): chemistry, acyl nitroso, nitroxyl, reactive oxygen species, and cell signaling.Mouse cytomegalovirus immediate-early protein 1 binds with host cell repressors to relieve suppressive effects on viral transcription and replication during lytic infection.Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells.Analysis of expression of heat shock protein-90 (HSP90) and the effects of HSP90 inhibitor (17-AAG) in multiple myeloma.Role of epigenetics in modulation of immune response at the junction of host-pathogen interaction and danger molecule signaling.Decitabine and SAHA-induced apoptosis is accompanied by survivin downregulation and potentiated by ATRA in p53-deficient cells.Caspase-3 and caspase-6 cleave STAT1 in leukemic cellsDaxx is a transcriptional repressor of CCAAT/enhancer-binding protein betaThe novel histone deacetylase inhibitor, AR-42, inhibits gp130/Stat3 pathway and induces apoptosis and cell cycle arrest in multiple myeloma cells.Regulation of ICP0-null mutant herpes simplex virus type 1 infection by ND10 components ATRX and hDaxx.The synergy of panobinostat plus doxorubicin in acute myeloid leukemia suggests a role for HDAC inhibitors in the control of DNA repair.Vorinostat inhibits STAT6-mediated TH2 cytokine and TARC production and induces cell death in Hodgkin lymphoma cell linesPRIMA-1(MET) induces nucleolar accumulation of mutant p53 and PML nuclear body-associated proteins.Suberoylanilide hydroxamic acid potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis by suppressing nuclear factor-kappaB activation.Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.Analysis of histone deacetylase inhibitor, depsipeptide (FR901228), effect on multiple myeloma.The histone deacetylase inhibitor MS-275 induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia cells.Insight into glucocorticoid receptor signalling through interactome model analysis.Multi-omics profiling reveals a distinctive epigenome signature for high-risk acute promyelocytic leukemia.Combination Phototherapy with a Histone Deacetylase Inhibitor and a Potent DNA-Binding Bibenzimidazole: Effects in Haematological Cell LinesTumor-selective action of HDAC inhibitors involves TRAIL induction in acute myeloid leukemia cells
P2860
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P2860
Histone deacetylase inhibitors induce caspase-dependent apoptosis and downregulation of daxx in acute promyelocytic leukaemia with t(15;17).
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Histone deacetylase inhibitors ...... promyelocytic leukaemia with t
@nl
Histone deacetylase inhibitors ...... cytic leukaemia with t(15;17).
@en
type
label
Histone deacetylase inhibitors ...... promyelocytic leukaemia with t
@nl
Histone deacetylase inhibitors ...... cytic leukaemia with t(15;17).
@en
prefLabel
Histone deacetylase inhibitors ...... promyelocytic leukaemia with t
@nl
Histone deacetylase inhibitors ...... cytic leukaemia with t(15;17).
@en
P2093
P2860
P1476
Histone deacetylase inhibitors ...... cytic leukaemia with t(15;17).
@en
P2093
P2860
P304
P356
10.1046/J.1365-2141.2001.03123.X
P407
P577
2001-11-01T00:00:00Z