Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.
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Transcriptional Targeting in Cancer Gene TherapyGene Therapy for Pediatric Cancer: State of the Art and Future PerspectivesMDM2 negatively regulates the human telomerase RNA gene promoterTelomere and Telomerase Therapeutics in CancerTherapeutic targeting of replicative immortalityThymosin β10 expression driven by the human TERT promoter induces ovarian cancer-specific apoptosis through ROS productionEstablishment of a transgenic zebrafish line for superficial skin ablation and functional validation of apoptosis modulators in vivoNovel therapeutic approaches for various cancer types using a modified sleeping beauty-based gene delivery systemNatural and pharmacological regulation of telomeraseProperties of a telomerase-specific Cre/Lox switch for transcriptionally targeted cancer gene therapy.Telomerase as a novel and potentially selective target for cancer chemotherapy.Targeting telomerase-expressing cancer cells.Telomerase and its potential for therapeutic intervention.Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies.Targeting telomerase for cancer therapeuticsFrontiers in Suicide Gene Therapy of Cancer.Telomerase inhibition in cancer therapeutics: molecular-based approachesTelomere biology of pediatric cancer.Telomerase and the endocrine system.Is telomerase a viable target in cancer?Telomerase and drug resistance in cancer.Role of Mesenchymal Stem Cells in Cancer Development and Their Use in Cancer Therapy.Replication-deficient rSV40 mediate pancreatic gene transfer and long-term inhibition of tumor growth.Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms.The hTERT and hTERC telomerase gene promoters are activated by the second exon of the adenoviral protein, E1A, identifying the transcriptional corepressor CtBP as a potential repressor of both genes.Antitumor effect of cytosine deaminase/5-fluorocytosine suicide gene therapy system mediated by Bifidobacterium infantis on melanoma.Tumor-specific adenoviral gene therapy: transcriptional repression of gene expression by utilizing p53-signal transduction pathways.Using intron splicing trick for preferential gene expression in transduced cells: an approach for suicide gene therapy.Involvement of NF-Y and Sp1 binding sequences in basal transcription of the human telomerase RNA gene.Escherichia coli-nitroreductase suicide gene control of human telomerase reverse transcriptase-transduced minor histocompatibility antigen-specific cytotoxic T cells.Telomerase reverse transcriptase (TERT) expression and proliferation in canine brain tumours.The intrabody targeting of hTERT attenuates the immortality of cancer cells.
P2860
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P2860
Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年学术文章
@wuu
2001年学术文章
@zh
2001年学术文章
@zh-cn
2001年学术文章
@zh-hans
2001年学术文章
@zh-my
2001年学术文章
@zh-sg
2001年學術文章
@yue
2001年學術文章
@zh-hant
name
Telomerase-specific suicide ge ...... cells to the pro-drug CB1954.
@en
Telomerase-specific suicide ge ...... cells to the pro-drug CB1954.
@nl
type
label
Telomerase-specific suicide ge ...... cells to the pro-drug CB1954.
@en
Telomerase-specific suicide ge ...... cells to the pro-drug CB1954.
@nl
prefLabel
Telomerase-specific suicide ge ...... cells to the pro-drug CB1954.
@en
Telomerase-specific suicide ge ...... cells to the pro-drug CB1954.
@nl
P2093
P2860
P356
P1433
P1476
Telomerase-specific suicide ge ...... r cells to the pro-drug CB1954
@en
P2093
P2860
P2888
P304
P356
10.1038/SJ.ONC.1204954
P407
P577
2001-11-01T00:00:00Z
P5875
P6179
1018077615