about
Telomere maintenance and dysfunction predict recurrence in paediatric ependymomaTelomerase and breast cancerTargeting TGF-β signaling in cancerTelomerase inhibitor Imetelstat (GRN163L) limits the lifespan of human pancreatic cancer cellsReciprocal regulation by TLR4 and TGF-β in tumor-initiating stem-like cells.Identification of a quinoxaline derivative that is a potent telomerase inhibitor leading to cellular senescence of human cancer cells.Natural and pharmacological regulation of telomeraseTargeting human telomerase for cancer therapeutics.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Targeted therapies for killing tumor cells.Lung cancer. 9: Molecular biology of lung cancer: clinical implications.Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands.Alternative splicing regulation of telomerase: a new paradigm?Advances in the molecular design of potential anticancer agents via targeting of human telomeric DNA.Telomerase as a therapeutic target for malignant gliomas.Combination of telomerase antisense oligonucleotides simultaneously targeting hTR and hTERT produces synergism of inhibition of telomerase activity and growth in human colon cancer cell lineTiptoeing to chromosome tips: facts, promises and perils of today's human telomere biology.Properties of a telomerase-specific Cre/Lox switch for transcriptionally targeted cancer gene therapy.Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin.Biophysical and biological properties of quadruplex oligodeoxyribonucleotidesFunctionalized halloysite nanotube-based carrier for intracellular delivery of antisense oligonucleotides.Telomere maintenance in childhood primitive neuroectodermal brain tumors.Telomeres, telomerase, and apoptosis.Targeting telomerase-expressing cancer cells.Drug insight: Cancer cell immortality-telomerase as a target for novel cancer gene therapies.Antitumor mechanism of antisense cantide targeting human telomerase reverse transcriptase.Role of Telomeres and Telomerase in Aging and Cancer.Is telomerase a viable target in cancer?Mechanism of human telomerase inhibition by BIBR1532, a synthetic, non-nucleosidic drug candidate.Targeting telomerase with radiolabeled inhibitors.New dimeric carbazole-benzimidazole mixed ligands for the stabilization of human telomeric G-quadruplex DNA and as telomerase inhibitors. A remarkable influence of the spacer.Intracellular efficacy of tumor-targeting group I intron-based trans-splicing ribozyme.An investigation of G-quadruplex structural polymorphism in the human telomere using a combined approach of hydrodynamic bead modeling and molecular dynamics simulation.Validation of tissue-specific promoter-driven tumor-targeting trans-splicing ribozyme system as a multifunctional cancer gene therapy device in vivo.Binding of G-quadruplex-interactive agents to distinct G-quadruplexes induces different biological effects in MiaPaCa cells.In-silico modeling studies of G-quadruplex with soy isoflavones having anticancerous activity.Telomerase-specific suicide gene therapy vectors expressing bacterial nitroreductase sensitize human cancer cells to the pro-drug CB1954.Inducible immortality in hTERT-human mesenchymal stem cells.Inhibitors of telomerase and poly(ADP-ribose) polymerases synergize to limit the lifespan of pancreatic cancer cells.Ex vivo expanded telomerase-specific T cells are effective in an orthotopic mouse model for pancreatic adenocarcinoma.
P2860
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P2860
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Telomerase inhibitors.
@ast
Telomerase inhibitors.
@en
Telomerase inhibitors.
@nl
type
label
Telomerase inhibitors.
@ast
Telomerase inhibitors.
@en
Telomerase inhibitors.
@nl
prefLabel
Telomerase inhibitors.
@ast
Telomerase inhibitors.
@en
Telomerase inhibitors.
@nl
P1476
Telomerase inhibitors.
@en
P2093
P304
P356
10.1016/S0167-7799(00)01541-9
P577
2001-03-01T00:00:00Z