Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas.
about
Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetesStrategies to achieve conditional gene mutation in miceGenetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancerLiver-specific inactivation of the Nrf1 gene in adult mouse leads to nonalcoholic steatohepatitis and hepatic neoplasiapdx-1 function is specifically required in embryonic beta cells to generate appropriate numbers of endocrine cell types and maintain glucose homeostasisBeta-cell-specific ablation of the hepatocyte growth factor receptor results in reduced islet size, impaired insulin secretion, and glucose intoleranceGenetic rescue of Cdk4 null mice restores pancreatic beta-cell proliferation but not homeostatic cell numberConditional inactivation of the MEN1 gene leads to pancreatic and pituitary tumorigenesis but does not affect normal development of these tissuesSSTR5 ablation in islet results in alterations in glucose homeostasis in micePancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and massAblation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo.Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations.Reprogramming of pancreatic beta cells into induced pluripotent stem cellsGamma-protocadherins regulate the functional integrity of hypothalamic feeding circuitry in mice.Glucose intolerance and impaired insulin secretion in pancreas-specific signal transducer and activator of transcription-3 knockout mice are associated with microvascular alterations in the pancreas.LKB1 deletion with the RIP2.Cre transgene modifies pancreatic beta-cell morphology and enhances insulin secretion in vivo.Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy.Serotonin regulates pancreatic beta cell mass during pregnancy.Beta-cell specific deletion of Dicer1 leads to defective insulin secretion and diabetes mellitus.Islet beta-cell-specific MafA transcription requires the 5'-flanking conserved region 3 control domain.Generation and characterization of Ins1-cre-driver C57BL/6N for exclusive pancreatic beta cell-specific Cre-loxP recombination.Novel transgenic mice for inducible gene overexpression in pancreatic cells define glucocorticoid receptor-mediated regulations of beta cells.Beneficial metabolic effects caused by persistent activation of beta-cell M3 muscarinic acetylcholine receptors in transgenic mice.Conditional gene targeting in mouse pancreatic ß-Cells: analysis of ectopic Cre transgene expression in the brain.ß-Cell-specific pyruvate dehydrogenase deficiency impairs glucose-stimulated insulin secretionTargeted inactivation of kinesin-1 in pancreatic β-cells in vivo leads to insulin secretory deficiency.RIP2-mediated LKB1 deletion causes axon degeneration in the spinal cord and hind-limb paralysis.Pancreatic T cell protein-tyrosine phosphatase deficiency affects beta cell function in miceIn vivo derivation of glucose-competent pancreatic endocrine cells from bone marrow without evidence of cell fusion.Insulin feedback action on pancreatic beta-cell function.Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow agingA single-nucleotide polymorphism in serine-threonine kinase 11, the gene encoding liver kinase B1, is a risk factor for multiple sclerosisGαi/o-coupled receptor signaling restricts pancreatic β-cell expansionCapricious Cre: the devil is in the detailsDICER Inactivation Identifies Pancreatic β-Cell "Disallowed" Genes Targeted by MicroRNAs.The IRE1α/XBP1s Pathway Is Essential for the Glucose Response and Protection of β Cells.Brain fatty acid synthase activates PPARalpha to maintain energy homeostasis.Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cellsProbing cell type-specific functions of Gi in vivo identifies GPCR regulators of insulin secretion.Dysregulation of Dicer1 in beta cells impairs islet architecture and glucose metabolism.
P2860
Q24564844-A3CF0499-74B5-46E3-821C-2DB3FC3B2F9EQ27023444-09955B12-5FAC-45FB-88F6-2B585CDC392DQ27355520-91F2B4EB-CD6E-47B2-A712-64C556192A28Q28237402-1CB4B802-4513-4FE1-9361-18D32E0ABB8AQ28504532-7E1C1E7D-DDD9-468E-BE61-550FA014EA7BQ28506581-5935F18D-4C5E-4CF5-B567-4958B808AC6EQ28584893-FEF0B56B-598C-411D-A9A2-B16BE9B2C441Q28589655-EE286367-17D7-4BB4-88A0-ADD27D36BED2Q28592142-E73CC4D9-49A5-4760-9CF9-704B5727B6A0Q30490044-38E2BF2D-BEF1-4685-AA79-B905846A5B7DQ30618321-1C85D149-E1D7-4E43-9BCE-4CB7E9288727Q33425920-651E1430-02BD-43A4-8612-91FF824185B6Q33641629-1A3A8F96-378D-41A1-8EEF-54C8E118B6EAQ33663961-F07A6FA6-905C-4270-920B-DBE917AD8CB0Q33848248-43CEAE80-FE86-4F21-BA45-4E11204835D3Q33916529-D03D6579-894F-45B4-BCFC-7DF5A2993D49Q33934670-DE9CF5A4-912F-49CC-9CB6-4DA32B8B4F7AQ34065652-87CBD5DE-DADD-48A6-BC4D-0A7DDF53952DQ34117281-49BF0B2D-1D67-491E-894A-F9CF8090D084Q34119780-C7A4FD02-FAE6-44F0-9BF6-568D014E246FQ34163825-9E079920-8896-4AB5-AE99-A03A173087D0Q34169923-73475CE8-ECA7-4880-92C5-7126FF14773CQ34197823-CB291A48-FDED-4802-BE23-314088CD7C2EQ34355241-6F980693-E777-4C18-8C9A-8453027B2E4CQ34426012-BF945A91-7527-4FC7-B248-74124CA2F055Q34448753-AD113128-BD9A-4F02-906A-9AC44F50A167Q34611758-7FF3B28E-7AD5-4C36-9C55-3506EE04220FQ34644615-592DA754-C5CC-4AF1-A598-3FC767E10C86Q34967985-50100762-6421-45BE-B47F-7606F28C5F93Q35013067-DB53C740-E522-4D95-9A01-6743BDFD29C3Q35080610-28CAA0AF-24C5-4E42-850D-0A76540BA93DQ35126302-6ED37BD6-2591-4DA6-BBC7-EC22807926A0Q35157007-787AE9BE-6632-483F-B98D-C2510997983FQ35762709-40B25D03-A1BF-42F2-BBC8-BF952476ECDEQ35794964-00EDAD03-C440-4041-ACE3-04E9CB331596Q35808715-FB578CDC-4D96-48B2-83FF-5DDC437BFBBDQ35921527-A07B60DF-6940-4B66-A575-7A5DDD9E8945Q36038188-42D8E4D7-2795-4F33-9F7E-74AB6C5DF8D2Q36121784-762E1511-592D-46C6-95C4-A6526CF83984Q36237692-00358943-0CB4-4CCD-BC5D-431DC9B7DCA8
P2860
Analysis of the Cre-mediated recombination driven by rat insulin promoter in embryonic and adult mouse pancreas.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年学术文章
@wuu
2000年学术文章
@zh
2000年学术文章
@zh-cn
2000年学术文章
@zh-hans
2000年学术文章
@zh-my
2000年学术文章
@zh-sg
2000年學術文章
@yue
2000年學術文章
@zh-hant
name
Analysis of the Cre-mediated r ...... onic and adult mouse pancreas.
@en
Analysis of the Cre-mediated r ...... onic and adult mouse pancreas.
@nl
type
label
Analysis of the Cre-mediated r ...... onic and adult mouse pancreas.
@en
Analysis of the Cre-mediated r ...... onic and adult mouse pancreas.
@nl
prefLabel
Analysis of the Cre-mediated r ...... onic and adult mouse pancreas.
@en
Analysis of the Cre-mediated r ...... onic and adult mouse pancreas.
@nl
P2093
P2860
P1433
P1476
Analysis of the Cre-mediated r ...... onic and adult mouse pancreas.
@en
P2093
P2860
P304
P356
10.1002/(SICI)1526-968X(200002)26:2<139::AID-GENE12>3.0.CO;2-7
P577
2000-02-01T00:00:00Z