Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
about
SCF(β-TRCP)-mediated degradation of NEDD4 inhibits tumorigenesis through modulating the PTEN/Akt signaling pathwayTherapeutic Implications of Targeting AKT Signaling in MelanomaPTEN plasticity: how the taming of a lethal gene can go too farRegulation of glioma migration and invasion via modification of Rap2a activity by the ubiquitin ligase Nedd4-1.Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.Oncogenic role of the E3 ubiquitin ligase NEDD4-1, a PTEN negative regulator, in non-small-cell lung carcinomas.Ubiquitin becomes ubiquitous in cancer: emerging roles of ubiquitin ligases and deubiquitinases in tumorigenesis and as therapeutic targets.Nedd4-1 is an exceptional prognostic biomarker for gastric cardia adenocarcinoma and functionally associated with metastasis.KDM5B is overexpressed in gastric cancer and is required for gastric cancer cell proliferation and metastasis.NEDD4L is downregulated in colorectal cancer and inhibits canonical WNT signaling.NEDD4-1 regulates migration and invasion of glioma cells through CNrasGEF ubiquitination in vitro.NEDD4 ubiquitin ligase is a putative oncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signalingIs NEDD4-1 a negative regulator of phosphatase and tensin homolog in gastric carcinogenesis?Copy number variation of E3 ubiquitin ligase genes in peripheral blood leukocyte and colorectal cancer.The PTEN-AKT3 signaling cascade as a therapeutic target in melanoma.Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.NEDD4 E3 ligase inhibits the activity of the Hippo pathway by targeting LATS1 for degradation.E3 ubiquitin ligases in cancer and implications for therapies.NEDD4-1 protects against ischaemia/reperfusion-induced cardiomyocyte apoptosis via the PI3K/Akt pathway.Intestinal knockout of Nedd4 enhances growth of Apcmin tumors.
P2860
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P2860
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
@en
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
@nl
type
label
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
@en
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
@nl
prefLabel
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
@en
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
@nl
P2093
P2860
P1476
Expression of NEDD4-1, a PTEN regulator, in gastric and colorectal carcinomas.
@en
P2093
Eun Goo Jeong
Min Sung Kim
Nam Jin Yoo
Sug Hyung Lee
Sung Soo Kim
P2860
P304
P356
10.1111/J.1600-0463.2008.00999.X
P577
2008-09-01T00:00:00Z