Modification of adenoviral vectors with polyethylene glycol modulates in vivo tissue tropism and gene expression.
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PEGylated Adenoviruses: From Mice to MonkeysCircumventing antivector immunity: potential use of nonhuman adenoviral vectorsIn vivo bioluminescent imaging of influenza a virus infection and characterization of novel cross-protective monoclonal antibodies.Peptide-based technologies to alter adenoviral vector tropism: ways and means for systemic treatment of cancerChemical modification with high molecular weight polyethylene glycol reduces transduction of hepatocytes and increases efficacy of intravenously delivered oncolytic adenovirusInfection and killing of multiple myeloma by adenovirusesEffects of shielding adenoviral vectors with polyethylene glycol on vector-specific and vaccine-mediated immune responses.Silk-elastin-like hydrogel improves the safety of adenovirus-mediated gene-directed enzyme-prodrug therapy.Characterization of species C human adenovirus serotype 6 (Ad6)Species differences in the pharmacology and toxicology of PEGylated helper-dependent adenovirusGeneration of a Kupffer cell-evading adenovirus for systemic and liver-directed gene transfer.Tumor vascular targeted delivery of polymer-conjugated adenovirus vector for cancer gene therapyIncreasing the efficacy of oncolytic adenovirus vectorsEnhancing the therapeutic efficacy of adenovirus in combination with biomaterials.Protection of adenovirus from neutralizing antibody by cationic PEG derivative ionically linked to adenovirusT-cell-biased immune responses generated by a mucosally targeted adenovirus-σ1 vaccineEvaluation of polymer shielding for adenovirus serotype 6 (Ad6) for systemic virotherapy against human prostate cancers.Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo.Limitations of Adenoviral Vector-Mediated Delivery of Gold Nanoparticles to Tumors for Hyperthermia Induction.Strategies to overcome host immunity to adenovirus vectors in vaccine development.Oncolytic (replication-competent) adenoviruses as anticancer agents.Innate immunity to adenovirus.CD46-mediated transduction of a species D adenovirus vaccine improves mucosal vaccine efficacy.Therapeutic potential of adenoviral vectors for delivery of expressed RNAi activators.Advances and future challenges in adenoviral vector pharmacology and targeting.Manipulation of adenovirus interactions with host factors for gene therapy applications.Management of malignant pleural effusion by suicide gene therapy in advanced stage lung cancer: a case series and literature review.Utilizing adenovirus vectors for gene delivery in cancer.The evolution of adenoviral vectors through genetic and chemical surface modifications.Tropism-modification strategies for targeted gene delivery using adenoviral vectors.Retargeting FX-binding-ablated HAdV-5 to vascular cells by inclusion of the RGD-4C peptide in hexon hypervariable region 7 and the HI loop.Efficient lung orthotopic tumor-growth suppression of oncolytic adenovirus complexed with RGD-targeted bioreducible polymer.Gene therapy with helper-dependent adenoviral vectors: lessons from studies in large animal models.PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice.Visualizing the replication of respiratory syncytial virus in cells and in living mice.Imaging luciferase-expressing viruses.Short-term rescue of neonatal lethality in a mouse model of propionic acidemia by gene therapy.PEGylated helper-dependent adenoviral vector expressing human Apo A-I for gene therapy in LDLR-deficient mice.Chemical conjugation of cowpea mosaic viruses with reactive HPMA-based polymers.An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood.
P2860
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P2860
Modification of adenoviral vectors with polyethylene glycol modulates in vivo tissue tropism and gene expression.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh-hant
name
Modification of adenoviral vec ...... e tropism and gene expression.
@en
Modification of adenoviral vec ...... e tropism and gene expression.
@nl
type
label
Modification of adenoviral vec ...... e tropism and gene expression.
@en
Modification of adenoviral vec ...... e tropism and gene expression.
@nl
prefLabel
Modification of adenoviral vec ...... e tropism and gene expression.
@en
Modification of adenoviral vec ...... e tropism and gene expression.
@nl
P2093
P356
P1433
P1476
Modification of adenoviral vec ...... e tropism and gene expression.
@en
P2093
Elena V Shashkova
Eric A Weaver
Michael A Barry
Reeti Khare
Sean E Hofherr
P304
P356
10.1038/MT.2008.86
P577
2008-05-06T00:00:00Z