The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth.
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Mutations in USP9X are associated with X-linked intellectual disability and disrupt neuronal cell migration and growthNonsense-mediated mRNA decay: novel mechanistic insights and biological impactNonsense-mediated mRNA decay: inter-individual variability and human diseaseNonsense-mediated mRNA decay in humans at a glanceNonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the StoryThe exon junction complex in neural development and neurodevelopmental disease.USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors.Viperin is an important host restriction factor in control of Zika virus infectionIntellectual disability and autism spectrum disorders: causal genes and molecular mechanisms.Identification of SMG6 cleavage sites and a preferred RNA cleavage motif by global analysis of endogenous NMD targets in human cells.Full UPF3B function is critical for neuronal differentiation of neural stem cells.A critical role of RBM8a in proliferation and differentiation of embryonic neural progenitors.The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.Increased abundance of translation machinery in stem cell-derived neural progenitor cells from four schizophrenia patients.Antisense oligonucleotide-directed inhibition of nonsense-mediated mRNA decayPosttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway.Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes.Modeling Fragile X syndrome in neurogenesis: An unexpected phenotype and a novel tool for future therapies.Depletion of the Fragile X Mental Retardation Protein in Embryonic Stem Cells Alters the Kinetics of Neurogenesis.Neurogenesis: Regulation by Alternative Splicing and Related Posttranscriptional Processes.From Gene to Behavior: L-Type Calcium Channel Mechanisms Underlying Neuropsychiatric Symptoms.Stress and the nonsense-mediated RNA decay pathway.Control of gene expression through the nonsense-mediated RNA decay pathway.Genetic and epigenetic methylation defects and implication of the ERMN gene in autism spectrum disorders.The Neuropsychiatric Disease-Associated Gene cacna1c Mediates Survival of Young Hippocampal NeuronsNonsense-mediated mRNA decay at the crossroads of many cellular pathwaysDual function of UPF3B in early and late translation termination.RNA degradation drives stem cell differentiation.Nonsense-Mediated RNA Decay Influences Human Embryonic Stem Cell Fate.A Upf3b-mutant mouse model with behavioral and neurogenesis defects.RNA decay, evolution, and the testis.Upf proteins: highly conserved factors involved in nonsense mRNA mediated decay.What can Cortical Development in Attention-Deficit/Hyperactivity Disorder Teach us About the Early Developmental Mechanisms Involved?An RNA decay factor wears a new coat: UPF3B modulates translation termination.HCFC1 loss-of-function mutations disrupt neuronal and neural progenitor cells of the developing brain.C-terminal short arginine/serine repeat sequence-dependent regulation of Y14 (RBM8A) localization.Nonsense-mediated mRNA decay: a 'nonsense' pathway makes sense in stem cell biology.Control of CNS functions by RNA-binding proteins in neurological diseases
P2860
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P2860
The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth.
description
2013 nî lūn-bûn
@nan
2013年の論文
@ja
2013年学术文章
@wuu
2013年学术文章
@zh
2013年学术文章
@zh-cn
2013年学术文章
@zh-hans
2013年学术文章
@zh-my
2013年学术文章
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2013年學術文章
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name
The UPF3B gene, implicated in ...... aviour and neuronal outgrowth.
@en
The UPF3B gene, implicated in ...... aviour and neuronal outgrowth.
@nl
type
label
The UPF3B gene, implicated in ...... aviour and neuronal outgrowth.
@en
The UPF3B gene, implicated in ...... aviour and neuronal outgrowth.
@nl
prefLabel
The UPF3B gene, implicated in ...... aviour and neuronal outgrowth.
@en
The UPF3B gene, implicated in ...... aviour and neuronal outgrowth.
@nl
P2860
P50
P921
P356
P1476
The UPF3B gene, implicated in ...... aviour and neuronal outgrowth.
@en
P2093
Claire C Homan
Reuben Jacob
P2860
P304
P356
10.1093/HMG/DDT315
P577
2013-07-02T00:00:00Z