Phenotype conversion from rheumatoid arthritis to systemic lupus erythematosus by introduction of Yaa mutation into FcγRIIB-deficient C57BL/6 mice.
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Lupus nephritis progression in FcγRIIB-/-yaa mice is associated with early development of glomerular electron dense deposits and loss of renal DNase I in severe disease.The presence of FCGR2B promoter or transmembrane region variant alleles leads to reduced serum IL-6 levels in rheumatoid arthritis.BXSB-type genome causes murine autoimmune glomerulonephritis: pathological correlation between telomeric region of chromosome 1 and Yaa.
P2860
Phenotype conversion from rheumatoid arthritis to systemic lupus erythematosus by introduction of Yaa mutation into FcγRIIB-deficient C57BL/6 mice.
description
2013 nî lūn-bûn
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Phenotype conversion from rheu ...... cγRIIB-deficient C57BL/6 mice.
@en
Phenotype conversion from rheu ...... cγRIIB-deficient C57BL/6 mice.
@nl
type
label
Phenotype conversion from rheu ...... cγRIIB-deficient C57BL/6 mice.
@en
Phenotype conversion from rheu ...... cγRIIB-deficient C57BL/6 mice.
@nl
prefLabel
Phenotype conversion from rheu ...... cγRIIB-deficient C57BL/6 mice.
@en
Phenotype conversion from rheu ...... cγRIIB-deficient C57BL/6 mice.
@nl
P2093
P2860
P356
P1476
Phenotype conversion from rheu ...... cγRIIB-deficient C57BL/6 mice.
@en
P2093
Hirofumi Amano
Hiromichi Tsurui
Hiroyuki Nishimura
Keiko Nishikawa
Norihiro Tada
Qingshun Lin
Sachiko Hirose
Shinya Kawano
Toshikazu Shirai
Toshiyuki Kaneko
P2860
P304
P356
10.1002/EJI.201243057
P407
P577
2013-01-25T00:00:00Z