Unusual function of the activation loop in the protein kinase DYRK1A.
about
Direct association of Sprouty-related protein with an EVH1 domain (SPRED) 1 or SPRED2 with DYRK1A modifies substrate/kinase interactionsOverexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosomeStructures of Down Syndrome Kinases, DYRKs, Reveal Mechanisms of Kinase Activation and Substrate RecognitionThe protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation siteTransient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling.Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE.Identification of a DYRK1A Inhibitor that Induces Degradation of the Target Kinase using Co-chaperone CDC37 fused with Luciferase nanoKAZ.DYRK1A haploinsufficiency causes a new recognizable syndrome with microcephaly, intellectual disability, speech impairment, and distinct facies.Ten new cases further delineate the syndromic intellectual disability phenotype caused by mutations in DYRK1A.Evolutionary constraints associated with functional specificity of the CMGC protein kinases MAPK, CDK, GSK, SRPK, DYRK, and CK2alpha.Activation, regulation, and inhibition of DYRK1A.MNB/DYRK1A as a multiple regulator of neuronal development.Mechanism of dual specificity kinase activity of DYRK1A.Identification of Plant Homologues of Dual Specificity Yak1-Related Kinases
P2860
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P2860
Unusual function of the activation loop in the protein kinase DYRK1A.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年学术文章
@wuu
2003年学术文章
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2003年学术文章
@zh-cn
2003年学术文章
@zh-hans
2003年学术文章
@zh-my
2003年学术文章
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2003年學術文章
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2003年學術文章
@zh-hant
name
Unusual function of the activation loop in the protein kinase DYRK1A.
@en
Unusual function of the activation loop in the protein kinase DYRK1A.
@nl
type
label
Unusual function of the activation loop in the protein kinase DYRK1A.
@en
Unusual function of the activation loop in the protein kinase DYRK1A.
@nl
prefLabel
Unusual function of the activation loop in the protein kinase DYRK1A.
@en
Unusual function of the activation loop in the protein kinase DYRK1A.
@nl
P2093
P50
P1476
Unusual function of the activation loop in the protein kinase DYRK1A.
@en
P2093
Hanna Czajkowska
Joachim Grötzinger
Katrin de Graaf
Stephan Wiechmann
P304
P356
10.1016/S0006-291X(03)00148-7
P407
P577
2003-03-01T00:00:00Z