about
Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPasesCharacterization of cyclin L1 as an immobile component of the splicing factor compartmentSequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinasesCloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinasesThe adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factorsIdentification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1ASelectivity Profiling and Biological Activity of Novel β-Carbolines as Potent and Selective DYRK1 Kinase InhibitorsCloning of a novel member (ARL5) of the ARF-family of Ras-related GTPasesLeptin induces inflammation-related genes in RINm5F insulinoma cellscDNA cloning and characterization of rat Clk3, a LAMMER kinase predominately expressed in testisDyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIIIThe protein kinase DYRK1A phosphorylates the splicing factor SF3b1/SAP155 at Thr434, a novel in vivo phosphorylation siteCharacterization of the human DYRK1A promoter and its regulation by the transcription factor E2F1.Mechanism of attenuation of leptin signaling under chronic ligand stimulation.Development of a sensitive non-radioactive protein kinase assay and its application for detecting DYRK activity in Xenopus laevis oocytesThe Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiationExtracellular ATP activates NFAT-dependent gene expression in neuronal PC12 cells via P2X receptorsNGF upregulates the plasminogen activation inhibitor-1 in neurons via the calcineurin/NFAT pathway and the Down syndrome-related proteins DYRK1A and RCAN1 attenuate this effectTransient expression of Mnb/Dyrk1a couples cell cycle exit and differentiation of neuronal precursors by inducing p27KIP1 expression and suppressing NOTCH signaling.JIP60, a methyl jasmonate-induced ribosome-inactivating protein involved in plant stress reactions.Activation, regulation, and inhibition of DYRK1A.Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control.Hyperleptinemia, leptin resistance, and polymorphic leptin receptor in the New Zealand obese mouse.Long-term and rapid regulation of ob mRNA levels in adipose tissue from normal (Sprague Dawley rats) and obese (db/db mice, fa/fa rats) rodents.The Down syndrome candidate dual-specificity tyrosine phosphorylation-regulated kinase 1A phosphorylates the neurodegeneration-related septin 4.A complex interaction pattern of CIS and SOCS2 with the leptin receptor.Pleiotropy of leptin receptor signalling is defined by distinct roles of the intracellular tyrosines.Alternative splicing variants of dual specificity tyrosine phosphorylated and regulated kinase 1B exhibit distinct patterns of expression and functional properties.DYRK1 is a co-activator of FKHR (FOXO1a)-dependent glucose-6-phosphatase gene expression.DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain.Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.Effect of tyrosine autophosphorylation on catalytic activity and subcellular localisation of homeodomain-interacting protein kinases (HIPK).10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.Comparison of the effects of insulin, PDGF, interleukin-6, and interferon-gamma on glucose transport in 3T3-L1 cells: lack of cross-talk between tyrosine kinase receptors and JAK/STAT pathways.Cloning and functional characterization of the ovine malic enzyme promoter.Characterisation of the mouse diabetes susceptibilty locus Nidd/SJL: islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat.Effect of hyperinsulinemia and type 2 diabetes-like hyperglycemia on expression of hepatic cytochrome p450 and glutathione s-transferase isoforms in a New Zealand obese-derived mouse backcross population.Unusual function of the activation loop in the protein kinase DYRK1A.Differential hepatic gene expression in a polygenic mouse model with insulin resistance and hyperglycemia: evidence for a combined transcriptional dysregulation of gluconeogenesis and fatty acid synthesis.
P50
Q24304366-C7E3ADD0-0760-4A6B-BB53-294F19531DD8Q24305313-77B66111-B624-4ABD-9D13-70763FED034BQ24316021-F7062E9F-9D82-40D7-BA61-3FDCCA125926Q28118261-DE287573-33D8-4386-B877-59C02234E367Q28118783-E820E4CE-E487-475D-96C8-DD21A4B6C96EQ28185216-ED9B26EC-945B-412B-85B1-9B533216AB4FQ28362375-BEE2178E-D896-40AE-9FA6-8BB08CC9E8B0Q28546672-BA29BBD0-0740-4076-98BE-EFAA2D33C5D3Q28572293-682830C4-D57B-4A3A-B244-6D8BFB296A29Q28575890-E8AC2083-4BE5-4003-8624-53744E181CADQ28577066-FCCC6F60-EB91-450A-97CD-4EE54C48440BQ28583955-92D1B9A2-E9B6-4488-9980-CB93747FCDDCQ33235281-86EC5251-DDFB-4E2E-9972-5344340DBC41Q33325766-60AFBA77-12CA-40A8-A45D-9FA83711CA82Q33522778-91271F12-4BDF-4FC4-A04E-F19F226AE975Q33582691-8A65684C-3E8B-4BC9-821D-657E6BC2A195Q33952905-E84212E8-9362-4F06-9835-631223880E5BQ34029073-C9FB7BF1-07B2-400D-BF86-9C050F2AE936Q34794979-80A5CEFD-2A6A-4C3D-90B5-2582F68DED0AQ35001705-FD9C0CC9-24B7-4F09-9DCB-FA1895DA2F13Q35609522-F7F29EC3-076C-40ED-82C1-BDFF1AF7D0EAQ37815234-0BB41E59-BEB2-4236-8A43-EFD1DA903882Q38037304-3EC2588A-18A9-444F-BCAC-11DDB95B2B99Q38342642-9580206C-3320-4AC9-8257-E640C0A6D066Q38355780-E0474775-7469-4B6B-8B5D-4D0CB0185D00Q39927135-2B12F877-103F-4AF2-8B4D-A4180F40AA3FQ40282038-A2689A30-F370-46AB-B600-E919024BBD05Q40474479-94AB41E9-A104-4C1E-B9DC-40EC0A855FECQ40664458-C4148C38-0F3C-48C5-8347-E6B957CEC244Q40680092-61D21009-97FF-420C-B6C7-47D74B31D65EQ41124666-A8C87B6F-C772-4C71-9940-37EC095E3438Q41767041-DCD1BD3E-44DE-46E8-BFBF-B48ECD43FF5DQ41938670-7D957768-03CB-40E0-98AE-5252222DE7D2Q42353177-79888100-9B74-4CDA-8329-21EDEEC22123Q42806616-659A1306-DEC1-4B07-85A4-08CF348E46ABQ42807239-A03A97A0-8E44-46A9-8B74-8BA519DC880DQ44055643-C13038DE-CA36-4EB2-B9F5-5C7627AF577AQ44072192-90ABA807-239D-4767-B4C4-927E68EEA492Q44327100-6E45E161-5CAB-47C0-A596-FE3589FEB893Q44757848-F7CF401D-05BE-47C8-8B91-D5CA54447938
P50
description
hulumtues
@sq
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Walter Becker
@ast
Walter Becker
@en
Walter Becker
@es
Walter Becker
@nl
Walter Becker
@sl
والتر بيكر
@ar
type
label
Walter Becker
@ast
Walter Becker
@en
Walter Becker
@es
Walter Becker
@nl
Walter Becker
@sl
والتر بيكر
@ar
prefLabel
Walter Becker
@ast
Walter Becker
@en
Walter Becker
@es
Walter Becker
@nl
Walter Becker
@sl
والتر بيكر
@ar
P106
P1153
7402414074
P21
P31
P496
0000-0002-0347-4768