Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

about

Yeast, fish, fly--models to study the pathogenesis of proteinopathies and screen for interventions.

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Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

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2013 nî lūn-bûn

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2013年の論文

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2013年学术文章

@wuu

2013年学术文章

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2013年学术文章

@zh-cn

2013年学术文章

@zh-hans

2013年学术文章

@zh-my

2013年学术文章

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2013年學術文章

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2013年學術文章

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name

Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

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Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

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type

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label

Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

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Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

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prefLabel

Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

@en

Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

@nl

P1476

Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

@en

P2093

Jochen Walter

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P2860

BACE2 functions as an alternative alpha-secretase in cells

Robust central reduction of amyloid-β in humans with an orally available, non-peptidic β-secretase inhibitor

Control of peripheral nerve myelination by the beta-secretase BACE1

BACE1 deficiency causes altered neuronal activity and neurodegeneration.

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

Developing β-secretase inhibitors for treatment of Alzheimer's disease.

β-Secretase (BACE1) inhibition causes retinal pathology by vascular dysregulation and accumulation of age pigment.

Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential.

Identification and biology of β-secretase.

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435-437

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scholarly article

editorial

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10.1111/JNC.12200

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English

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127

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2013-03-25T00:00:00Z

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236079640

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23527866

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Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

about

P2860

P2860

Fishing for function--distinct roles of Bace1 and Bace2 in Zebrafish development.

description

name

type

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P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P577

P5875

P698